LCMT1

LCMT1 catalyzes the methylation of the carboxyl group of the C-terminal leucine residue (leu309) of the catalytic subunit of protein phosphatase-2A (PPP2CA; MIM 176915) (De Baere et al., 1999 [PubMed 10600115]).
Full Name
leucine carboxyl methyltransferase 1
Function
Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.
Biological Process
C-terminal protein methylationManual Assertion Based On ExperimentIDA:MGI
Cellular protein modification processManual Assertion Based On ExperimentTAS:ProtInc
G2/M transition of mitotic cell cycleTAS:Reactome
Negative regulation of protein-containing complex assemblyManual Assertion Based On ExperimentIMP:MGI
Protein methylationManual Assertion Based On ExperimentIMP:MGI
Regulation of apoptotic processManual Assertion Based On ExperimentIMP:MGI
Regulation of glucose metabolic processIEA:Ensembl
Regulation of mitotic cell cycle spindle assembly checkpointManual Assertion Based On ExperimentIMP:MGI
Cellular Location
Cytosol
Nucleoplasm
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Anti-LCMT1 antibodies

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Mouse Anti-LCMT1 Recombinant Antibody (2F8) (CBMAB-L0821-YJ)

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Target: LCMT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2F8
Application*: F, WB
Datasheet SDS

Mouse Anti-LCMT1 Recombinant Antibody (1E7) (CBMAB-L0816-YJ)

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Target: LCMT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1E7
Application*: F, WB
Datasheet SDS

Mouse Anti-LCMT1 Recombinant Antibody (CBYCL-159) (CBMAB-L0060-YC)

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Target: LCMT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBYCL-159
Application*: WB
Datasheet SDS

Mouse Anti-LCMT1 Recombinant Antibody (CBYCL-158) (CBMAB-L0059-YC)

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Target: LCMT1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYCL-158
Application*: E, WB
Datasheet SDS

Mouse Anti-Lcmt1 Recombinant Antibody (4A4) (CBMAB-L2873-YJ)

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Target: LCMT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse, Rat
Clone: 4A4
Application*: WB
Datasheet SDS

Mouse Anti-LCMT1 Recombinant Antibody (5D5) (CBMAB-L0825-YJ)

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Target: LCMT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5D5
Application*: WB
Datasheet SDS

Mouse Anti-LCMT1 Recombinant Antibody (4A5) (CBMAB-L0824-YJ)

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Target: LCMT1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 4A5
Application*: F, IF, IH, WB
Datasheet SDS

Mouse Anti-LCMT1 Recombinant Antibody (3F4) (CBMAB-L0823-YJ)

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Target: LCMT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3F4
Application*: F, IF, WB
Datasheet SDS

Mouse Anti-LCMT1 Recombinant Antibody (3D3) (CBMAB-L0822-YJ)

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Target: LCMT1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3D3
Application*: E, WB
Datasheet SDS

Mouse Anti-LCMT1 Recombinant Antibody (2C9) (CBMAB-L0820-YJ)

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Target: LCMT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 2C9
Application*: WB, P
Datasheet SDS

Mouse Anti-LCMT1 Recombinant Antibody (CBYJL-1264) (CBMAB-L0819-YJ)

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Target: LCMT1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJL-1264
Application*: F, IF, IH, WB
Datasheet SDS

Mouse Anti-LCMT1 Recombinant Antibody (CBYJL-1263) (CBMAB-L0818-YJ)

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Target: LCMT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1263
Application*: LA
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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