LCMT1

LCMT1 catalyzes the methylation of the carboxyl group of the C-terminal leucine residue (leu309) of the catalytic subunit of protein phosphatase-2A (PPP2CA; MIM 176915) (De Baere et al., 1999 [PubMed 10600115]).

leucine carboxyl methyltransferase 1

Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.

C-terminal protein methylationManual Assertion Based On ExperimentIDA:MGI
Cellular protein modification processManual Assertion Based On ExperimentTAS:ProtInc
G2/M transition of mitotic cell cycleTAS:Reactome
Negative regulation of protein-containing complex assemblyManual Assertion Based On ExperimentIMP:MGI
Protein methylationManual Assertion Based On ExperimentIMP:MGI
Regulation of apoptotic processManual Assertion Based On ExperimentIMP:MGI
Regulation of glucose metabolic processIEA:Ensembl
Regulation of mitotic cell cycle spindle assembly checkpointManual Assertion Based On ExperimentIMP:MGI

Cytosol
Nucleoplasm