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LECT2

LECT2 is a secreted, 16 kDa protein that acts as a chemotactic factor to neutrophils and stimulates the growth of chondrocytes and osteoblasts. This protein has high sequence similarity to the chondromodulin repeat regions of the chicken myb-induced myeloid 1 protein. A polymorphism in this gene may be associated with rheumatoid arthritis.

Full Name

Leukocyte Cell Derived Chemotaxin 2

Function

Has a neutrophil chemotactic activity. Also a positive regulator of chondrocyte proliferation (PubMed:9524238).
Does not show metalloendopeptidase activity (PubMed:27334921).

Biological Process

ChemotaxisManual Assertion Based On ExperimentTAS:ProtInc
Skeletal system developmentManual Assertion Based On ExperimentTAS:ProtInc

Cellular Location

Cytoplasm
Secreted

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Anti-LECT2 antibodies

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Mouse Anti-LECT2 Recombinant Antibody (CBYCL-213) (CBMAB-L0114-YC)

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Target: LECT2

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBYCL-213

Application*: E

Mouse Anti-LECT2 Recombinant Antibody (MM0449-4B24) (CBMAB-L1039-YJ)

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Target: LECT2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: MM0449-4B24

Application*: WB

Mouse Anti-LECT2 Recombinant Antibody (G2A5) (CBMAB-L1038-YJ)

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Target: LECT2

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: G2A5

Application*: IP

Mouse Anti-LECT2 Recombinant Antibody (5C5) (CBMAB-L1036-YJ)

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Target: LECT2

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 5C5

Application*: WB

Mouse Anti-LECT2 Recombinant Antibody (3G9) (CBMAB-L1034-YJ)

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Target: LECT2

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 3G9

Application*: E

Mouse Anti-LECT2 Recombinant Antibody (CBYJL-1388) (CBMAB-L1033-YJ)

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Target: LECT2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJL-1388

Application*: WB, P

Mouse Anti-LECT2 Recombinant Antibody (CBYJL-1386) (CBMAB-L1031-YJ)

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Target: LECT2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJL-1386

Application*: WB

Human LECT2 ELISA Kit (V2LY-0626-LY2767)

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Target: LECT2

Sensitivity: 0.26 ng/mL

Detection Range: 0.5-200 ng/mL

Sample Type: Serum, Plasma, cell culture supernates

Specificity: Human

Assay Type: Sandwich

Reactivity: Human

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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