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LPA

The protein encoded by this gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I.

Full Name

S. aureus MAGI2

Function

Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1. Lp(a) may be a ligand for megalin/Gp 330.

Biological Process

Blood circulationManual Assertion Based On ExperimentTAS:ProtInc
Lipid metabolic process1 PublicationNAS:ProtInc
Lipid transportIEA:UniProtKB-KW
ProteolysisManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Extracellular region
Extracellular space
Extrinsic component of plasma membrane
Plasma lipoprotein particle

PTM

N- and O-glycosylated. The N-glycans are complex biantennary structures present in either a mono- or disialylated state. The O-glycans are mostly (80%) represented by the monosialylated core type I structure, NeuNAcalpha2-3Galbeta1-3GalNAc, with smaller amounts of disialylated and non-sialylated O-glycans also detected.

Anti-LPA antibodies

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-LPA Recombinant Antibody (CBFYM-1221) (CBMAB-M1378-FY)

SDS

Target: LPA

Host: Mouse

Antibody Isotype: IgG2b, λ

Specificity: Human

Clone: CBFYM-1221

Application*: E, WB

Mouse Anti-LPA Recombinant Antibody (CBYCL-434) (CBMAB-L0335-YC)

SDS

Target: LPA

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYCL-434

Application*: E, P, WB

Mouse Anti-LPA Recombinant Antibody (CBYCL-433) (CBMAB-L0334-YC)

SDS

Target: LPA

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYCL-433

Application*: WB, IC, P, C, E

Mouse Anti-LPA Recombinant Antibody (4H1) (CBMAB-L1945-YJ)

SDS

Target: LPA

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 4H1

Application*: E, IC, IF, P, WB

Mouse Anti-LPA Recombinant Antibody (CBYJL-1914) (CBMAB-L1944-YJ)

SDS

Target: LPA

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJL-1914

Application*: E, IC, IH, WB

Goat Anti-Lpa Monoclonal Antibody (CBFYR0677) (CBMAB-R0677-FY)

SDS

Target: LPA

Host: Goat

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYR0677

Mouse Anti-LPA Recombinant Antibody (8F6A9, 8H5C5) (CBMAB-AO703LY)

SDS

Target: LPA

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 8F6A9, 8H5C5

Application*: ELISA, WB, IHC

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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