LPA

The protein encoded by this gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I.
Full Name
S. aureus MAGI2
Function
Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1. Lp(a) may be a ligand for megalin/Gp 330.
Biological Process
Blood circulationManual Assertion Based On ExperimentTAS:ProtInc
Lipid metabolic process1 PublicationNAS:ProtInc
Lipid transportIEA:UniProtKB-KW
ProteolysisManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Extracellular region
Extracellular space
Extrinsic component of plasma membrane
Plasma lipoprotein particle
PTM
N- and O-glycosylated. The N-glycans are complex biantennary structures present in either a mono- or disialylated state. The O-glycans are mostly (80%) represented by the monosialylated core type I structure, NeuNAcalpha2-3Galbeta1-3GalNAc, with smaller amounts of disialylated and non-sialylated O-glycans also detected.
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Anti-LPA antibodies

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Goat Anti-Lpa Monoclonal Antibody (CBFYR0677) (CBMAB-R0677-FY)

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Target: LPA
Host: Goat
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYR0677
Datasheet SDS

Mouse Anti-LPA Recombinant Antibody (CBFYM-1221) (CBMAB-M1378-FY)

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Target: LPA
Host: Mouse
Antibody Isotype: IgG2b, λ
Specificity: Human
Clone: CBFYM-1221
Application*: E, WB
Datasheet SDS

Mouse Anti-LPA Recombinant Antibody (CBYCL-434) (CBMAB-L0335-YC)

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Target: LPA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYCL-434
Application*: E, P, WB
Datasheet SDS

Mouse Anti-LPA Recombinant Antibody (CBYCL-433) (CBMAB-L0334-YC)

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Target: LPA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYCL-433
Application*: WB, IC, P, C, E
Datasheet SDS

Mouse Anti-LPA Recombinant Antibody (4H1) (CBMAB-L1945-YJ)

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Target: LPA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4H1
Application*: E, IC, IF, P, WB
Datasheet SDS

Mouse Anti-LPA Recombinant Antibody (CBYJL-1914) (CBMAB-L1944-YJ)

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Target: LPA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1914
Application*: E, IC, IH, WB
Datasheet SDS

Mouse Anti-LPA Recombinant Antibody (CBT164) (V2LY-0625-LY3748)

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Target: LPA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT164
Application*: WB, P, IF, E
Datasheet SDS

Mouse Anti-LPA Recombinant Antibody (CBT4733) (V2LY-0625-LY2748)

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Target: LPA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4733
Application*: IH, IC
Datasheet SDS

Mouse Anti-LPA Recombinant Antibody (CBT4510) (V2LY-0625-LY2267)

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Target: LPA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4510
Application*: IH
Datasheet SDS

Mouse Anti-LPA Recombinant Antibody (8F6A9, 8H5C5) (CBMAB-AO703LY)

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Target: LPA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 8F6A9, 8H5C5
Application*: ELISA, WB, IHC
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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