LSM10

LSM10 appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to U7 snRNA. LSM10 binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner.
Full Name
LSM10, U7 small nuclear RNA associated
Function
Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to U7 snRNA. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner.
Biological Process
mRNA 3'-end processing by stem-loop binding and cleavageManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of G1/S transition of mitotic cell cycleManual Assertion Based On ExperimentIMP:UniProtKB
RNA splicingIEA:UniProtKB-KW
Cellular Location
Nucleus
PTM
Not methylated. Methylation is not necessary for interaction with SMN.
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Anti-LSM10 antibodies

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Mouse Anti-LSM10 Recombinant Antibody (CBYCL-504) (CBMAB-L0405-YC)

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Target: LSM10
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYCL-504
Application*: WB
Datasheet SDS

Mouse Anti-LSM10 Recombinant Antibody (CBYJL-2064) (CBMAB-L2198-YJ)

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Target: LSM10
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-2064
Application*: WB
Datasheet SDS

Mouse Anti-LSM10 Recombinant Antibody (2522C1a) (CBMAB-L2197-YJ)

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Target: LSM10
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2522C1a
Application*: DB, IC
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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