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MYCBP

The protein encoded by this gene binds to the N-terminus of the oncogenic protein C-MYC, enhancing the ability of C-MYC to activate E box-dependent transcription. The encoded protein is normally found in the cytoplasm, but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC. This protein may be involved in spermatogenesis. This gene can be silenced by microRNA-22. Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene. [provided by RefSeq, Nov 2011]

Full Name

MYC Binding Protein

Function

May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC.

Biological Process

Regulation of transcription, DNA-templated Source: UniProtKB
Spermatogenesis Source: UniProtKB

Cellular Location

Cytoplasm
Nucleus
Mitochondrion
Note: Translocates into the nucleus in the S phase of the cell cycle upon an increase of MYC expression. Found in the mitochondria when associated with AKAP1.

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Anti-MYCBP antibodies

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Mouse Anti-MYCBP Recombinant Antibody (A1265) (CBMAB-AP4946LY)

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Target: MYCBP

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: A1265

Application*: ELISA, IHC

Mouse Anti-MYCBP Recombinant Antibody (CB276A) (CBMAB-CA276LY)

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Target: MYCBP

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CB276A

Application*: ELISA, IHC

Mouse Anti-MYCBP Recombinant Antibody (1B12) (CBMAB-A5714-LY)

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Target: MYCBP

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 1B12

Application*: WB, E

Mouse Anti-MYCBP Recombinant Antibody (2E9) (CBMAB-A5713-LY)

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Target: MYCBP

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 2E9

Application*: WB, E

Mouse Anti-MYCBP Recombinant Antibody (1D5D5) (CBMAB-R4276-CN)

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Target: MYCBP

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: 1D5D5

Application*: E, IH

Mouse Anti-MYCBP Recombinant Antibody (CBFYM-2894) (CBMAB-M3088-FY)

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Target: MYCBP

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBFYM-2894

Application*: E, WB, IH

Mouse Anti-MYCBP (AA 34-103) Recombinant Antibody (CBFYM-2893) (CBMAB-M3087-FY)

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Target: MYCBP

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBFYM-2893

Application*: E, WB

Mouse Anti-MYCBP Recombinant Antibody (CBFYM-2892) (CBMAB-M3086-FY)

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Target: MYCBP

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYM-2892

Application*: DB

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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