MYH2

Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction.
Full Name
MYH2
Function
Muscle contraction. Required for cytoskeleton organization (By similarity).
Biological Process
Muscle contraction Source: BHF-UCL
Muscle filament sliding Source: BHF-UCL
Cellular Location
Other locations
myofibril
Note: Thick filaments of the myofibrils.
Involvement in disease
Myopathy, proximal, with ophthalmoplegia (MYPOP):
A muscular disorder characterized by mild-to-moderate muscle weakness, ophthalmoplegia, and contractures at birth in some patients. Muscle biopsies from patients show predominance of type 1 fibers and small or absent type 2A fibers. The disease is non-progressive or it progresses very slowly. Inheritance is autosomal dominant or recessive.
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Anti-MYH2 antibodies

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Mouse Anti-MYH2 Antibody (BF-35) (CBMAB-1438CQ)

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Target: MYH2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Cattle, Dog, Horse, Cat, Goat, Guinea pig, Human, Pig, Rodent
Clone: BF-35
Application*: IF, IH, WB
Datasheet SDS

Mouse Anti-MYH2 Antibody (BF-32) (CBMAB-1437CQ)

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Target: MYH2
Host: Mouse
Antibody Isotype: IgM
Specificity: Cattle, Human, Sheep, Rodent
Clone: BF-32
Application*: IF, IH, WB
Datasheet SDS

Mouse Anti-MYH2 Recombinant Antibody (CBFYM-2932) (CBMAB-M3127-FY)

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Target: MYH2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rabbit, Rat
Clone: CBFYM-2932
Application*: IH, WB
Datasheet SDS

Mouse Anti-MYH2 Recombinant Antibody (CBFYM-0438) (CBMAB-M0553-FY)

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Target: MYH2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat, Rabbit
Clone: CBFYM-0438
Application*: E, IH, IF, P
Datasheet SDS

Mouse Anti-MYH2 Recombinant Antibody (A4.74) (CBMAB-0335-CN)

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Target: MYH2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Cattle, C. elegans, Horse, Llama, Pig, Quail, Rodent
Clone: A4.74
Application*: E, IF, IH, IP, WB
Datasheet SDS

Mouse Anti-MYH2 Recombinant Antibody (A4.1519) (CBMAB-0334-CN)

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Target: MYH2
Host: Mouse
Antibody Isotype: IgM
Specificity: Human, Pig, Rodent
Clone: A4.1519
Application*: E, IF, IH, IP, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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