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NAV1

This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants.

Full Name

neuron navigator 1

Function

May be involved in neuronal migration.

Biological Process

Microtubule bundle formation Source: GO_Central
Nervous system development Source: GO_Central
Neuron migration Source: GO_Central

Cellular Location

Cytoskeleton
Note: Associates with a subset of microtubule plus ends. Enriched in neuronal growth cones (By similarity).

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Anti-NAV1 antibodies

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Rat Anti-NAV1 Recombinant Antibody (KT124) (CBMAB-N1234-WJ)

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Target: NAV1

Host: Rat

Antibody Isotype: IgG2a

Specificity: Human

Clone: KT124

Application*: WB, IC

Mouse Anti-NAV1 Recombinant Antibody (G-12) (CBMAB-N1233-WJ)

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Target: NAV1

Host: Mouse

Specificity: Human

Clone: G-12

Application*: WB, IP, IF, E

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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