NMT2

N-myristoyltransferase (NMT) catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It transfers myristic acid from myristoyl coenzyme A to the amino group of a protein's N-terminal glycine residue. Biochemical evidence indicates the presence of several distinct NMTs, varying in apparent molecular weight and /or subcellular distribution. The predicted 498-amino acid of human NMT2 protein shares 77% and 96% sequence identity with human NMT1 and mouse Nmt2 comprise two distinct families of N-myristoyltransferases. [provided by RefSeq]
Full Name
N-myristoyltransferase 2
Function
Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins (PubMed:25255805, PubMed:9506952).
Also able to mediate N-terminal lysine myristoylation of proteins: catalyzes myristoylation of ARF6 on both 'Gly-2' and 'Lys-3' (PubMed:32103017).
Lysine myristoylation is required to maintain ARF6 on membranes during the GTPase cycle (PubMed:32103017).
Biological Process
Intracellular transport of virusTAS:Reactome
N-terminal peptidyl-glycine N-myristoylationManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of rhodopsin mediated signaling pathwayTAS:Reactome
Cellular Location
Cytoplasm
Membrane
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Anti-NMT2 antibodies

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Mouse Anti-NMT2 Recombinant Antibody (2E12-4B5) (CBMAB-A6030-LY)

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Target: NMT2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2E12-4B5
Application*: WB, E
Datasheet SDS

Rabbit Anti-NMT2 Recombinant Antibody (CBWJN-1454) (CBMAB-N2833-WJ)

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Target: NMT2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBWJN-1454
Application*: WB, P, F, IC
Datasheet SDS

Mouse Anti-NMT2 Recombinant Antibody (CBWJN-0351) (CBMAB-N2832-WJ)

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Target: NMT2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJN-0351
Application*: WB, IF
Datasheet SDS

Mouse Anti-NMT2 Recombinant Antibody (CBWJN-0340) (CBMAB-N2831-WJ)

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Target: NMT2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJN-0340
Application*: E, WB
Datasheet SDS

Mouse Anti-NMT2 Recombinant Antibody (2B4) (CBMAB-N2830-WJ)

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Target: NMT2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2B4
Application*: WB, IH
Datasheet SDS

Mouse Anti-NMT2 Recombinant Antibody (2A5) (CBMAB-N2829-WJ)

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Target: NMT2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat, Mouse
Clone: 2A5
Application*: IH, WB
Datasheet SDS

Mouse Anti-NMT2 Recombinant Antibody (1H7) (CBMAB-N2827-WJ)

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Target: NMT2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1H7
Application*: WB
Datasheet SDS

Mouse Anti-NMT2 Recombinant Antibody (1G3) (CBMAB-N2826-WJ)

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Target: NMT2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1G3
Application*: WB, IH, P
Datasheet SDS

Mouse Anti-NMT2 Recombinant Antibody (1B4) (CBMAB-N2823-WJ)

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Target: NMT2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1B4
Application*: WB, IH
Datasheet SDS

Mouse Anti-NMT2 Recombinant Antibody (1B11) (CBMAB-N2822-WJ)

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Target: NMT2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1B11
Application*: WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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