NRBF2

May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro).
Full Name
Nuclear Receptor Binding Factor 2
Function
May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro).
Involved in starvation-induced autophagy probably by its association with PI3K complex I (PI3KC3-C1). However, effects has been described variably. Involved in the induction of starvation-induced autophagy (PubMed:24785657).
Stabilzes PI3KC3-C1 assembly and enhances ATG14-linked lipid kinase activity of PIK3C3 (By similarity).
Proposed to negatively regulate basal and starvation-induced autophagy and to inhibit PIK3C3 activity by modulating interactions in PI3KC3-C1 (PubMed:25086043).
May be involved in autophagosome biogenesis (PubMed:25086043).
May play a role in neural progenitor cell survival during differentiation (By similarity).
Biological Process
AutophagyManual Assertion Based On ExperimentIMP:GO_Central
Regulation of lipid kinase activityIEA:Ensembl
Response to endoplasmic reticulum stressIEA:Ensembl
Cellular Location
Nucleus
Cytoplasm
Cytoplasmic vesicle
Cytoplasmic vesicle, autophagosome
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Anti-NRBF2 antibodies

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Rabbit Anti-NRBF2 Recombinant Antibody (D8G1) (CBMAB-N3537-WJ)

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Target: NRBF2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Monkey, Hamster, Cattle, Dog, Horse
Clone: D8G1
Application*: WB, IP
Datasheet SDS

Mouse Anti-NRBF2 Recombinant Antibody (CBWJN-1542) (CBMAB-N3536-WJ)

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Target: NRBF2
Host: Mouse
Specificity: Human
Clone: CBWJN-1542
Application*: WB
Datasheet SDS

Mouse Anti-NRBF2 Recombinant Antibody (1B2) (CBMAB-N3528-WJ)

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Target: NRBF2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1B2
Application*: WB
Datasheet SDS

Mouse Anti-NRBF2 Recombinant Antibody (1A8) (CBMAB-N3527-WJ)

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Target: NRBF2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1A8
Application*: WB, IH
Datasheet SDS

Mouse Anti-NRBF2 Recombinant Antibody (V2-177993) (CBMAB-N3525-WJ)

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Target: NRBF2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: V2-177993
Application*: WB
Datasheet SDS

Mouse Anti-NRBF2 Recombinant Antibody (CBWJN-0323) (CBMAB-N0520-WJ)

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Target: NRBF2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJN-0323
Application*: DB, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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