NRBF2

May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro).

Nuclear Receptor Binding Factor 2

May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro).
Involved in starvation-induced autophagy probably by its association with PI3K complex I (PI3KC3-C1). However, effects has been described variably. Involved in the induction of starvation-induced autophagy (PubMed:24785657).
Stabilzes PI3KC3-C1 assembly and enhances ATG14-linked lipid kinase activity of PIK3C3 (By similarity).
Proposed to negatively regulate basal and starvation-induced autophagy and to inhibit PIK3C3 activity by modulating interactions in PI3KC3-C1 (PubMed:25086043).
May be involved in autophagosome biogenesis (PubMed:25086043).
May play a role in neural progenitor cell survival during differentiation (By similarity).

AutophagyManual Assertion Based On ExperimentIMP:GO_Central
Regulation of lipid kinase activityIEA:Ensembl
Response to endoplasmic reticulum stressIEA:Ensembl

Nucleus
Cytoplasm
Cytoplasmic vesicle
Cytoplasmic vesicle, autophagosome