NUTM1

NUTM1 (NUT Midline Carcinoma Family Member 1) is a Protein Coding gene. Diseases associated with NUTM1 include Nut Midline Carcinoma and Extragonadal Nonseminomatous Germ Cell Tumor. Among its related pathways are Chromatin Regulation / Acetylation. An important paralog of this gene is NUTM2G.
Full Name
NUT Midline Carcinoma Family Member 1
Function
Plays a role in the regulation of proliferation. Regulates TERT expression by modulating SP1 binding to TERT promoter binding sites.
Cellular Location
Cytoplasm
Nucleus
Shuttles between nucleus and cytoplasm.
Involvement in disease
A chromosomal aberration involving NUTM1 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with BRD4 which produces a BRD4-NUTM1 fusion protein.
A chromosomal aberration involving NUTM1 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;9)(q14;q34) with BRD3 which produces a BRD3-NUTM1 fusion protein.
PTM
Methylated at Gln-1046 by N6AMT1.
Phosphorylation on Ser-1026, Ser-1029 or Ser-1031 is important for cytoplasmic export.
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Anti-NUTM1 antibodies

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Rabbit Anti-NUTM1 Recombinant Antibody (C52B1) (CBMAB-N4050-WJ)

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Target: NUTM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Rat, Monkey
Clone: C52B1
Application*: WB, IP, P, IF
Datasheet SDS

Mouse Anti-NUTM1 Recombinant Antibody (8B1) (CBMAB-A0937-LY)

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Target: NUTM1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: 8B1
Application*: WB, E
Datasheet SDS

Mouse Anti-NUTM1 Recombinant Antibody (8B1) (CBMAB-C9050-LY)

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Target: NUTM1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 8B1
Application*: E, WB
Datasheet SDS

Mouse Anti-NUTM1 Recombinant Antibody (2B6) (CBMAB-N0572-WJ)

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Target: NUTM1
Host: Mouse
Antibody Isotype: IgG, κ
Specificity: Human, Mouse
Clone: 2B6
Application*: WB, IH, IF, P
Datasheet SDS

Mouse Anti-NUTM1 Recombinant Antibody (1G6) (CBMAB-N0571-WJ)

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Target: NUTM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: 1G6
Application*: WB, IH, IF, P
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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