OR5T1

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Full Name

Olfactory Receptor Family 5 Subfamily T Member 1

Function

Odorant receptor.

Cellular Location

Cell membrane

Topology

Extracellular: 1-37
Helical: 38-58
Cytoplasmic: 59-66
Helical: 67-87
Extracellular: 88-111
Helical: 112-132
Cytoplasmic: 133-151
Helical: 152-172
Extracellular: 173-208
Helical: 209-229
Cytoplasmic: 230-249
Helical: 250-270
Extracellular: 271-283
Helical: 284-304
Cytoplasmic: 305-326