OXSR1
The product of this gene belongs to the Ser/Thr protein kinase family of proteins. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton. [provided by RefSeq, Jul 2008]
Full Name
Oxidative Stress Responsive 1
Function
Phosphorylates RELL1, RELL2 and RELT (PubMed:16389068, PubMed:28688764).
Phosphorylates PAK1 (PubMed:14707132).
Phosphorylates PLSCR1 in the presence of RELT (PubMed:22052202).
Phosphorylates PAK1 (PubMed:14707132).
Phosphorylates PLSCR1 in the presence of RELT (PubMed:22052202).
Biological Process
Cellular hypotonic responseIEA:Ensembl
Cellular response to chemokineManual Assertion Based On ExperimentIMP:BHF-UCL
Chemokine (C-C motif) ligand 21 signaling pathwayBy SimilarityISS:BHF-UCL
Chemokine (C-X-C motif) ligand 12 signaling pathwayManual Assertion Based On ExperimentIMP:BHF-UCL
Intracellular signal transductionManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of potassium ion transmembrane transporter activityIEA:Ensembl
Osmosensory signaling pathwayManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Peptidyl-threonine phosphorylationManual Assertion Based On ExperimentIDA:ParkinsonsUK-UCL
Positive regulation of T cell chemotaxisManual Assertion Based On ExperimentIMP:BHF-UCL
Protein autophosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Protein phosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Response to oxidative stressManual Assertion Based On ExperimentTAS:ProtInc
Signal transductionManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Cellular response to chemokineManual Assertion Based On ExperimentIMP:BHF-UCL
Chemokine (C-C motif) ligand 21 signaling pathwayBy SimilarityISS:BHF-UCL
Chemokine (C-X-C motif) ligand 12 signaling pathwayManual Assertion Based On ExperimentIMP:BHF-UCL
Intracellular signal transductionManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of potassium ion transmembrane transporter activityIEA:Ensembl
Osmosensory signaling pathwayManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Peptidyl-threonine phosphorylationManual Assertion Based On ExperimentIDA:ParkinsonsUK-UCL
Positive regulation of T cell chemotaxisManual Assertion Based On ExperimentIMP:BHF-UCL
Protein autophosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Protein phosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Response to oxidative stressManual Assertion Based On ExperimentTAS:ProtInc
Signal transductionManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Cellular Location
Cytoplasm
PTM
Autophosphorylated.
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Anti-OXSR1 antibodies
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Target: OXSR1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: 6C7
Application*: WB, E
Target: OXSR1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3F6
Application*: WB, E
Target: OXSR1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 5G8
Application*: E, M
Target: OXSR1
Specificity: Human
Target: OXSR1
Specificity: Human
Target: OXSR1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1B9
Application*: E, IF, IH, WB
Target: OXSR1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Monkey, Rat
Clone: 1F3
Application*: IH, P, WB
Target: OXSR1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3A8
Application*: E, IF, P, WB
Target: OXSR1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4G9
Application*: E, P, WB
Target: OXSR1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4D12
Application*: E, IF, IP, WB
Target: OXSR1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1D10
Application*: E, IF, P
Target: OXSR1
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human
Clone: 1C8
Application*: E, IF, WB
Target: OXSR1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1F6
Application*: E, IC, IF, IP, WB
Target: OXSR1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: S1
Application*: E, WB
Target: OXSR1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2A5
Application*: E, WB
Target: OXSR1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4C12
Application*: E, IF, WB
Target: OXSR1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1B10
Application*: E, IP, WB
Target: OXSR1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXO-0103
Application*: E, IC, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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