PFDN6

PFDN6 is a subunit of the heteromeric prefoldin complex that chaperones nascent actin and alpha-and beta-tubulin chains pending their transfer to the cytosolic chaperonin containing TCP1.
Full Name
Prefoldin Subunit 6
Function
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
Biological Process
Chaperone-mediated protein complex assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of amyloid fibril formationManual Assertion Based On ExperimentIDA:FlyBase
Protein foldingManual Assertion Based On ExperimentIDA:FlyBase
Protein stabilization3 PublicationsIC:ComplexPortal
Cellular Location
chaperone complex
cytoplasm
prefoldin complex
RPAP3/R2TP/prefoldin-like complex
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Anti-PFDN6 antibodies

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Mouse Anti-PFDN6 Recombinant Antibody (4E10) (CBMAB-P1505-YC)

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Target: PFDN6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4E10
Application*: IH, F, WB
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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