PGD

6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies.

Full Name

PGD

Function

Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with concomitant reduction of NADP to NADPH.

Biological Process

D-gluconate catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Pentose biosynthetic processIEA:Ensembl
Pentose-phosphate shuntISS:UniProtKB
Pentose-phosphate shunt, oxidative branchManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Cytoplasm

Anti-PGD antibodies

Mouse Anti-PGD Recombinant Antibody (1B6) (CBMAB-0806-CN)

Datasheet

SDS

Target: PGD

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: 1B6

Application*: E, M

Rabbit Anti-PGD Recombinant Antibody (CBYC-P322) (CBMAB-P1567-YC)

Datasheet

SDS

Target: PGD

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBYC-P322

Application*: IC, IF

Mouse Anti-PGD Recombinant Antibody (46B3) (CBMAB-P1566-YC)

Datasheet

SDS

Target: PGD

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 46B3

Application*: WB, E, IC, IF

Mouse Anti-PGD Recombinant Antibody (2A5) (CBMAB-P1565-YC)

Datasheet

SDS

Target: PGD

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 2A5

Application*: WB, P, IF, IC

Mouse Anti-PGD Recombinant Antibody (1G12) (CBMAB-P1564-YC)

Datasheet

SDS

Target: PGD

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 1G12

Application*: E, IF, IH, WB

Mouse Anti-PGD Antibody (V2-5053) (CBMAB-0801-YC)

Datasheet

SDS

Target: PGD

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: V2-5053

Application*: E, IP

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)