loading...

PRDM2

PRDM2 is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action.

Full Name

PRDM2

Function

S-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates 'Lys-9' of histone H3. May function as a DNA-binding transcription factor. Binds to the macrophage-specific TPA-responsive element (MTE) of the HMOX1 (heme oxygenase 1) gene and may act as a transcriptional activator of this gene.

Biological Process

Determination of adult lifespanIEA:Ensembl
Negative regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:ARUK-UCL
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:NTNU_SB
Regulation of gene expressionManual Assertion Based On ExperimentIBA:GO_Central
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Regulation of transcription, DNA-templated2 PublicationsNAS:UniProtKB

Cellular Location

Nucleus

View more

Anti-PRDM2 antibodies

+ Filters

Loading...

Mouse Anti-PRDM2 Recombinant Antibody (RIZ1723) (CBMAB-R0655-CN)

Compare

Target: PRDM2

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: RIZ1723

Application*: ICC, IP

Mouse Anti-PRDM2 Recombinant Antibody (33AT1045) (CBMAB-R0654-CN)

Compare

Target: PRDM2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Mouse, Human

Clone: 33AT1045

Application*: WB, E

Mouse Anti-PRDM2 Antibody (2A4) (CBMAB-0864-YC)

Compare

Target: PRDM2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 2A4

Application*: IP, M

Mouse Anti-PRDM2 Antibody (2A1) (CBMAB-0863-YC)

Compare

Target: PRDM2

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 2A1

Application*: IP, WB, M

Human Recombinant RIZ1 protein, GST Tag-1 (V2LY-0526-LY6560)

Compare

Target: PRDM2

Expressed Host: E. coli

Sequence: Amino Acid: 1-200

Tag: GST Tag

Human Recombinant RIZ1 protein, GST Tag (V2LY-0526-LY6559)

Compare

Target: PRDM2

Expressed Host: Baculovirus-Insect Cells

Sequence: Amino Acid: 1-340

Tag: GST Tag

Human Recombinant RIZ1 protein (V2LY-0526-LY6558)

Compare

Target: PRDM2

Expressed Host: E. coli

Sequence: Amino Acid: 1-200

More Infomation

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

online inquiry

Online Inquiry