RABGAP1
RABGAP1 (RAB GTPase Activating Protein 1) is a Protein Coding gene. Diseases associated with RABGAP1 include Warburg Micro Syndrome 1. Among its related pathways are Vesicle-mediated transport and TBC/RABGAPs. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and Rab GTPase binding. An important paralog of this gene is RABGAP1L.
Full Name
RAB GTPase activating protein 1
Function
May act as a GTPase-activating protein of RAB6A. May play a role in microtubule nucleation by centrosome. May participate in a RAB6A-mediated pathway involved in the metaphase-anaphase transition.
Biological Process
Biological Process activation of GTPase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cell cycleIEA:UniProtKB-KW
Biological Process regulation of GTPase activityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process cell cycleIEA:UniProtKB-KW
Biological Process regulation of GTPase activityManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Cytoplasm, cytosol
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Predominantly cytosolic but also associated with the centrosome.
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Predominantly cytosolic but also associated with the centrosome.
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Anti-RABGAP1 antibodies
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Target: RABGAP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBCNR-082
Application*: WB
Target: RABGAP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1A8
Application*: E, IF, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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