RBFOX1

The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Full Name
RNA binding protein fox-1 homolog 1
Function
RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis.
Biological Process
mRNA processing
Nervous system development
Regulation of alternative mRNA splicing, via spliceosome
RNA splicing
RNA transport
Cellular Location
Nucleus; Cytoplasm
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Anti-RBFOX1 antibodies

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Mouse Anti-RBFOX1 Recombinant Antibody (4F9) (CBMAB-A0024-YC)

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Target: RBFOX1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4F9
Application*: WB, IH
Datasheet SDS

Mouse Anti-RBFOX1 Recombinant Antibody (CBMAB-BR428LY)

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Target: RBFOX1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Application*: IHC, WB
Datasheet SDS

Mouse Anti-RBFOX1 Recombinant Antibody (D8H8) (CBMAB-A0025-YC)

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Target: RBFOX1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: D8H8
Application*: WB, IH, IC, IF, P
Datasheet SDS

Mouse Anti-RBFOX1 Recombinant Antibody (CBXF-3293) (CBMAB-F3987-CQ)

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Target: RBFOX1
Host: Mouse
Antibody Isotype: IgG
Specificity: Cattle, Human, Mouse, Rat
Clone: CBXF-3293
Application*: IF, WB
Datasheet SDS

Mouse Anti-RBFOX1 Recombinant Antibody (CBXF-1829) (CBMAB-F3364-CQ)

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Target: RBFOX1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-1829
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-RBFOX1 (N-term) Recombinant Antibody (CBXF-3709) (CBMAB-F3231-CQ)

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Target: RBFOX1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Cattle, Mouse, Rat
Clone: CBXF-3709
Application*: E, IF, WB
Datasheet SDS

Mouse Anti-RBFOX1 Recombinant Antibody (CBXF-1026) (CBMAB-F1313-CQ)

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Target: RBFOX1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat, Cattle
Clone: CBXF-1026
Application*: WB, IF
Datasheet SDS

Mouse Anti-RBFOX1 Recombinant Antibody (3D12) (CBMAB-R1689-CN)

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Target: RBFOX1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3D12
Application*: WB
Datasheet SDS

Mouse Anti-RBFOX1 Recombinant Antibody (2D10) (CBMAB-R1688-CN)

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Target: RBFOX1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2D10
Application*: WB, IH
Datasheet SDS

Mouse Anti-RBFOX1 Recombinant Antibody (2C12) (CBMAB-R1687-CN)

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Target: RBFOX1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2C12
Application*: WB, IH
Datasheet SDS

Mouse Anti-RBFOX1 Recombinant Antibody (1F7) (CBMAB-R1685-CN)

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Target: RBFOX1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1F7
Application*: WB, IH
Datasheet SDS

Mouse Anti-RBFOX1 Recombinant Antibody (1F2) (CBMAB-R1684-CN)

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Target: RBFOX1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1F2
Application*: WB
Datasheet SDS

Mouse Anti-RBFOX1 Recombinant Antibody (1G10) (CBMAB-0772CQ)

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Target: RBFOX1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat, Cattle
Clone: 1G10
Application*: WB, IF
Datasheet SDS

Mouse Anti-RBFOX1 Recombinant Antibody (D8H8) (CBMAB-0771CQ)

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Target: RBFOX1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: D8H8
Application*: WB, IF, IH, P, IP
Datasheet SDS

Mouse Anti-RBFOX1 Recombinant Antibody (4F9) (CBMAB-0770CQ)

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Target: RBFOX1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4F9
Application*: WB, IH
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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