RBM45

This gene encodes a member of the RNA recognition motif (RRM)-type RNA-binding family of proteins. This protein exhibits preferential binding to poly(C) RNA. Initial cloning of this gene found that the rat ortholog was dynamically expressed in the developing rat brain. This protein has been localized to inclusion bodies in the brain and spinal cord of amyotrophic lateral sclerosis and Alzheimer's patients. A pseudogene has been identified on chromosome 8. [provided by RefSeq, Feb 2015]

RNA Binding Motif Protein 45

RNA-binding protein with binding specificity for poly(C). May play an important role in neural development.

Biological Process cell differentiationIEA:UniProtKB-KW
Biological Process nervous system developmentISS:UniProtKB

Cytoplasm
Nucleus
Predominantly cytoplasmic. May shuttle between cytoplasm and nucleus.