SH3GL2

SH3GL2 implicated in synaptic vesicle endocytosis and may recruit other proteins to membranes with high curvature. SH3GL2 required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 to mediate BDNF-NTRK2 early endocytic trafficking and signaling from early endosomes.
Full Name
SH3-domain GRB2-like 2
Function
Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 to mediate BDNF-NTRK2 early endocytic trafficking and signaling from early endosomes.
Biological Process
Biological Process cellular response to brain-derived neurotrophic factor stimulusISS:UniProtKB
Biological Process central nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Biological Process dendrite extensionISS:UniProtKB
Biological Process negative regulation of blood-brain barrier permeabilityManual Assertion Based On ExperimentIMP:ARUK-UCL
Biological Process negative regulation of gene expressionManual Assertion Based On ExperimentIMP:ARUK-UCL
Biological Process negative regulation of protein phosphorylationManual Assertion Based On ExperimentIMP:ARUK-UCL
Biological Process neuron projection developmentISS:UniProtKB
Biological Process signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process synaptic vesicle uncoatingManual Assertion Based On ExperimentIBA:GO_Central
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Anti-SH3GL2 antibodies

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Mouse Anti-SH3GL2 Recombinant Antibody (CBXS-3272) (CBMAB-S6012-CQ)

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Target: SH3GL2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Rat
Clone: CBXS-3272
Application*: E, IH, WB
Datasheet SDS

Mouse Anti-SH3GL2 Recombinant Antibody (2G6) (CBMAB-A8097-LY)

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Target: SH3GL2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Rat
Clone: 2G6
Application*: WB, E
Datasheet SDS

Mouse Anti-SH3GL2 Recombinant Antibody (CBXS-2860) (CBMAB-S5610-CQ)

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Target: SH3GL2
Host: Mouse
Specificity: Human
Clone: CBXS-2860
Application*: E, WB
Datasheet SDS

Rabbit Anti-SH3GL2 Recombinant Antibody (CBXS-1248) (CBMAB-S4107-CQ)

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Target: SH3GL2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBXS-1248
Application*: WB
Datasheet SDS

Rabbit Anti-SH3GL2 Recombinant Antibody (CBXS-1247) (CBMAB-S4106-CQ)

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Target: SH3GL2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBXS-1247
Application*: WB, IP, P, IF
Datasheet SDS

Rabbit Anti-SH3GL2 Recombinant Antibody (CBFYE-1645) (CBMAB-E2311-FY)

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Target: SH3GL2
Host: Rabbit
Specificity: Human, Mouse
Clone: CBFYE-1645
Application*: IF, IP, WB
Datasheet SDS

Mouse Anti-SH3GL2 Monoclonal Antibody (5A6) (CBMAB-1149-YC)

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Target: SH3GL2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Sheep, Human, Rat
Clone: 5A6
Application*: E, P, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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