SPOCK1
This gene encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The protein's function is unknown, although similarity to thyropin-type cysteine protease-inhibitors suggests its function may be related to protease inhibition.
Full Name
SPARC/Osteonectin, Cwcv And Kazal Like Domains Proteoglycan 1
Function
May play a role in cell-cell and cell-matrix interactions. May contribute to various neuronal mechanisms in the central nervous system.
Biological Process
Biological Process cell adhesion1 PublicationNAS:UniProtKB
Biological Process central nervous system neuron differentiationISS:UniProtKB
Biological Process negative regulation of cell-substrate adhesionManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of neuron projection developmentManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process nervous system development1 PublicationNAS:UniProtKB
Biological Process neurogenesisISS:UniProtKB
Biological Process neuron migrationISS:UniProtKB
Biological Process regulation of cell growth1 PublicationNAS:UniProtKB
Biological Process central nervous system neuron differentiationISS:UniProtKB
Biological Process negative regulation of cell-substrate adhesionManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of neuron projection developmentManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process nervous system development1 PublicationNAS:UniProtKB
Biological Process neurogenesisISS:UniProtKB
Biological Process neuron migrationISS:UniProtKB
Biological Process regulation of cell growth1 PublicationNAS:UniProtKB
Cellular Location
Secreted, extracellular space, extracellular matrix
PTM
O-glycosylated. Glycosaminoglycan that contains chondroitin sulfate and heparan sulfate.
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Anti-SPOCK1 antibodies
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Target: SPOCK1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-1682
Application*: WB, IP, IF, E
Target: SPOCK1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1681
Application*: WB, IP
Target: SPOCK1
Sensitivity: 0.027 ng/mL
Detection Range: 0.05-30 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: SPOCK1
Expressed Host: Baculovirus-Insect Cells
Sequence: Amino Acid: 1-439
Tag: His Tag
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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