SPOCK1

This gene encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The protein's function is unknown, although similarity to thyropin-type cysteine protease-inhibitors suggests its function may be related to protease inhibition.

Full Name

SPARC/Osteonectin, Cwcv And Kazal Like Domains Proteoglycan 1

Function

May play a role in cell-cell and cell-matrix interactions. May contribute to various neuronal mechanisms in the central nervous system.

Biological Process

Biological Process cell adhesion1 PublicationNAS:UniProtKB
Biological Process central nervous system neuron differentiationISS:UniProtKB
Biological Process negative regulation of cell-substrate adhesionManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of neuron projection developmentManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process nervous system development1 PublicationNAS:UniProtKB
Biological Process neurogenesisISS:UniProtKB
Biological Process neuron migrationISS:UniProtKB
Biological Process regulation of cell growth1 PublicationNAS:UniProtKB

Cellular Location

Secreted, extracellular space, extracellular matrix

PTM

O-glycosylated. Glycosaminoglycan that contains chondroitin sulfate and heparan sulfate.