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SPOCK1

This gene encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The protein's function is unknown, although similarity to thyropin-type cysteine protease-inhibitors suggests its function may be related to protease inhibition.
Full Name
SPARC/Osteonectin, Cwcv And Kazal Like Domains Proteoglycan 1
Function
May play a role in cell-cell and cell-matrix interactions. May contribute to various neuronal mechanisms in the central nervous system.
Biological Process
Biological Process cell adhesion1 PublicationNAS:UniProtKB
Biological Process central nervous system neuron differentiationISS:UniProtKB
Biological Process negative regulation of cell-substrate adhesionManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of neuron projection developmentManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process nervous system development1 PublicationNAS:UniProtKB
Biological Process neurogenesisISS:UniProtKB
Biological Process neuron migrationISS:UniProtKB
Biological Process regulation of cell growth1 PublicationNAS:UniProtKB
Cellular Location
Secreted, extracellular space, extracellular matrix
PTM
O-glycosylated. Glycosaminoglycan that contains chondroitin sulfate and heparan sulfate.

Anti-SPOCK1 antibodies

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Target: SPOCK1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-1682
Application*: WB, IP, IF, E
Target: SPOCK1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1681
Application*: WB, IP
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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