SRR
SRR (Serine Racemase) is a Protein Coding gene. Diseases associated with SRR include Streptococcal Meningitis and Vitamin E, Familial Isolated Deficiency Of. Among its related pathways are Metabolism and Glycine, serine and threonine metabolism. Gene Ontology (GO) annotations related to this gene include calcium ion binding and magnesium ion binding.
Full Name
Serine Racemase
Function
Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.
Biological Process
Biological Process agingIEA:Ensembl
Biological Process brain developmentIEA:Ensembl
Biological Process D-serine biosynthetic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process D-serine metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process L-serine metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process pyruvate biosynthetic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process response to lipopolysaccharideManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process response to morphineIEA:Ensembl
Biological Process response to xenobiotic stimulusIEA:Ensembl
Biological Process serine family amino acid metabolic processISS:UniProtKB
Biological Process brain developmentIEA:Ensembl
Biological Process D-serine biosynthetic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process D-serine metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process L-serine metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process pyruvate biosynthetic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process response to lipopolysaccharideManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process response to morphineIEA:Ensembl
Biological Process response to xenobiotic stimulusIEA:Ensembl
Biological Process serine family amino acid metabolic processISS:UniProtKB
Cellular Location
apical part of cell
cytoplasm
cytosol
neuronal cell body
plasma membrane
cytoplasm
cytosol
neuronal cell body
plasma membrane
PTM
S-nitrosylated, leading to decrease the enzyme activity.
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Anti-SRR antibodies
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Target: SRR
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 12B2
Application*: E, WB, F
Target: SRR
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-1427
Application*: WB, IP, IF
Target: SRR
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXS-0715
Application*: WB, IP
Target: SRR
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5265
Application*: F, IF, WB
Target: SRR
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5248
Application*: F, IH, P, WB
Target: SRR
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4775
Application*: F, IF, IH, P, WB
Target: SRR
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: CBXS-4538
Application*: WB, F, IH, IF, P
Target: SRR
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-4011
Application*: F, IH, P, WB
Target: SRR
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5884
Application*: F, IF, IH, P, WB
Target: SRR
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-5742
Application*: F, IH, P, WB
Target: SRR
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBXS-5636
Application*: WB
Target: SRR
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: BA0156
Application*: IF, IP, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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