SYT9

SYT9 (Synaptotagmin 9) is a Protein Coding gene. Diseases associated with SYT9 include Diabetes Mellitus, Permanent Neonatal. Among its related pathways are Protein-protein interactions at synapses and Clathrin-mediated endocytosis. Gene Ontology (GO) annotations related to this gene include calcium ion binding and transporter activity. An important paralog of this gene is SYT10.May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.

Full Name

Synaptotagmin 9

Function

May be involved in Ca2+-dependent exocytosis of secretory vesicles through Ca2+ and phospholipid binding to the C2 domain or may serve as Ca2+ sensors in the process of vesicular trafficking and exocytosis.

Biological Process

Biological Process calcium-dependent activation of synaptic vesicle fusionIEA:Ensembl
Biological Process calcium-ion regulated exocytosisIBA:GO_Central1 Publication
Biological Process cellular response to calcium ionIBA:GO_Central1 Publication
Biological Process positive regulation of calcium ion-dependent exocytosisIEA:Ensembl
Biological Process regulation of calcium ion-dependent exocytosisIBA:GO_Central1 Publication
Biological Process regulation of dopamine secretionIBA:GO_Central1 Publication
Biological Process regulation of insulin secretionIEA:Ensembl
Biological Process vesicle-mediated transportIBA:GO_Central1 Publication

Cellular Location

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane

Topology

Vesicular: 1-52
Helical: 53-73
Cytoplasmic: 74-491