TFDP3

TFDP3 is a member of the DP family of proteins, which form heterodimers with E2F proteins (see E2F1; MIM 189971) and regulate transcription (Qiao et al., 2007 [PubMed 17062573]).[supplied by OMIM

transcription factor Dp family, member 3

Competitive inhibitor of E2F-mediated transactivation activity. Impairs E2F-mediated cell-cycle progression from G1 to S phase.

Biological Process cellular response to DNA damage stimulusSource:UniProtKB1 Publication
Biological Process G1/S transition of mitotic cell cycleSource:InterPro
Biological Process negative regulation of DNA-binding transcription factor activitySource:UniProtKB1 Publication
Biological Process negative regulation of G1/S transition of mitotic cell cycleSource:UniProtKB1 Publication
Biological Process regulation of transcription by RNA polymerase IISource:GO_Central1 Publication

Nucleus
Cytoplasm
Translocates to the nucleus on heterodimerization with E2F family members.