TFDP3
TFDP3 is a member of the DP family of proteins, which form heterodimers with E2F proteins (see E2F1; MIM 189971) and regulate transcription (Qiao et al., 2007 [PubMed 17062573]).[supplied by OMIM
Full Name
transcription factor Dp family, member 3
Function
Competitive inhibitor of E2F-mediated transactivation activity. Impairs E2F-mediated cell-cycle progression from G1 to S phase.
Biological Process
Biological Process cellular response to DNA damage stimulusSource:UniProtKB1 Publication
Biological Process G1/S transition of mitotic cell cycleSource:InterPro
Biological Process negative regulation of DNA-binding transcription factor activitySource:UniProtKB1 Publication
Biological Process negative regulation of G1/S transition of mitotic cell cycleSource:UniProtKB1 Publication
Biological Process regulation of transcription by RNA polymerase IISource:GO_Central1 Publication
Biological Process G1/S transition of mitotic cell cycleSource:InterPro
Biological Process negative regulation of DNA-binding transcription factor activitySource:UniProtKB1 Publication
Biological Process negative regulation of G1/S transition of mitotic cell cycleSource:UniProtKB1 Publication
Biological Process regulation of transcription by RNA polymerase IISource:GO_Central1 Publication
Cellular Location
Nucleus
Cytoplasm
Translocates to the nucleus on heterodimerization with E2F family members.
Cytoplasm
Translocates to the nucleus on heterodimerization with E2F family members.
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Anti-TFDP3 antibodies
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Target: TFDP3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse
Clone: 3F11
Application*: WB, E
Target: TFDP3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1F11
Application*: WB, E
Target: TFDP3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJT-2660
Application*: E, IC, WB
Target: TFDP3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJT-2659
Application*: E, IF, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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