Mouse Anti-TFDP3 Recombinant Antibody (CBYJT-2659) (CBMAB-T1840-YJ)

Name: Mouse Anti-TFDP3 Recombinant Antibody (CBYJT-2659)
SKU: CBMAB-T1840-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBYJT-2659

Application

ELISA, IF, WB

Immunogen

Partial recombinant corresponding to aa1-101 from human TFDP3 (NP_057605) with GST tag. MW of the GST tag alone is 26kD

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.2

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 1-101

More Infomation

Target

Full Name

transcription factor Dp family, member 3

Introduction

TFDP3 is a member of the DP family of transcription factors. These factors heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. TFDP3 plays a role as a negative regulator and inhibits the DNA binding and transcriptional activities of E2F factors.

Entrez Gene ID

51270

UniProt ID

Q5H9I0

Alternative Names

Transcription Factor Dp Family Member 3; Cancer/Testis Antigen 30; Hepatocellular Carcinoma-Associated Antigen 661; E2F-Like Protein; HCA661; CT30; DP4; Transcription Factor Dp Family, Member 3

Function

Competitive inhibitor of E2F-mediated transactivation activity. Impairs E2F-mediated cell-cycle progression from G1 to S phase.

Biological Process

Biological Process cellular response to DNA damage stimulusSource:UniProtKB1 Publication
Biological Process G1/S transition of mitotic cell cycleSource:InterPro
Biological Process negative regulation of DNA-binding transcription factor activitySource:UniProtKB1 Publication
Biological Process negative regulation of G1/S transition of mitotic cell cycleSource:UniProtKB1 Publication
Biological Process regulation of transcription by RNA polymerase IISource:GO_Central1 Publication

Cellular Location

Nucleus
Cytoplasm
Translocates to the nucleus on heterodimerization with E2F family members.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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