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Mouse Anti-TFDP3 Recombinant Antibody (1F11) (CBMAB-A9038-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
1F11
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
TFDP3 (NP_057605, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
transcription factor Dp family, member 3
Introduction
TFDP3 is a member of the DP family of proteins, which form heterodimers with E2F proteins (see E2F1; MIM 189971) and regulate transcription (Qiao et al., 2007 [PubMed 17062573]).[supplied by OMIM
Entrez Gene ID
51270
UniProt ID
Q5H9I0
Alternative Names
CT30; E2F-like; HCA661; MGC161639
Function
Competitive inhibitor of E2F-mediated transactivation activity. Impairs E2F-mediated cell-cycle progression from G1 to S phase.
Biological Process
Biological Process cellular response to DNA damage stimulusSource:UniProtKB1 Publication
Biological Process G1/S transition of mitotic cell cycleSource:InterPro
Biological Process negative regulation of DNA-binding transcription factor activitySource:UniProtKB1 Publication
Biological Process negative regulation of G1/S transition of mitotic cell cycleSource:UniProtKB1 Publication
Biological Process regulation of transcription by RNA polymerase IISource:GO_Central1 Publication
Cellular Location
Nucleus
Cytoplasm
Translocates to the nucleus on heterodimerization with E2F family members.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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