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Mouse Anti-TFDP3 Recombinant Antibody (CBYJT-2660) (CBMAB-T1841-YJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-2660
Antibody Isotype
IgG2a
Application
ELISA, ICC, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Preservative
0.09% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-101

Target

Full Name
transcription factor Dp family, member 3
Introduction
TFDP3 is a member of the DP family of transcription factors. These factors heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. TFDP3 plays a role as a negative regulator and inhibits the DNA binding and transcriptional activities of E2F factors.
Entrez Gene ID
51270
UniProt ID
Q5H9I0
Alternative Names
Transcription Factor Dp Family Member 3; Cancer/Testis Antigen 30; Hepatocellular Carcinoma-Associated Antigen 661; E2F-Like Protein; HCA661; CT30; DP4; Transcription Factor Dp Family, Member 3
Function
Competitive inhibitor of E2F-mediated transactivation activity. Impairs E2F-mediated cell-cycle progression from G1 to S phase.
Biological Process
Biological Process cellular response to DNA damage stimulusSource:UniProtKB1 Publication
Biological Process G1/S transition of mitotic cell cycleSource:InterPro
Biological Process negative regulation of DNA-binding transcription factor activitySource:UniProtKB1 Publication
Biological Process negative regulation of G1/S transition of mitotic cell cycleSource:UniProtKB1 Publication
Biological Process regulation of transcription by RNA polymerase IISource:GO_Central1 Publication
Cellular Location
Nucleus
Cytoplasm
Translocates to the nucleus on heterodimerization with E2F family members.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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