VAT1

Synaptic vesicles are responsible for regulating the storage and release of neurotransmitters in the nerve terminal. The protein encoded by this gene is an abundant integral membrane protein of cholinergic synaptic vesicles and is thought to be involved in vesicular transport. It belongs to the quinone oxidoreductase subfamily of zinc-containing alcohol dehydrogenase proteins. [provided by RefSeq]

Full Name

vesicle amine transport protein 1 homolog (T. californica)

Function

Possesses ATPase activity (By similarity).
Plays a part in calcium-regulated keratinocyte activation in epidermal repair mechanisms. Has no effect on cell proliferation. Negatively regulates mitochondrial fusion in cooperation with mitofusin proteins (MFN1-2).

Biological Process

Biological Process negative regulation of mitochondrial fusion Source:UniProtKB1 Publication

Cellular Location

Cytoplasm
Mitochondrion outer membrane
The majority is localized in the cytoplasm and a small amount is associated with mitochondria.

Anti-VAT1 antibodies

Mouse Anti-VAT1 Recombinant Antibody (CBYY-1554) (CBMAB-1624-YY)

Datasheet

SDS

Target: VAT1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBYY-1554

Application*: WB, E

Mouse Anti-VAT1 Recombinant Antibody (CBYY-1286) (CBMAB-1304-YY)

Datasheet

SDS

Target: VAT1

Host: Mouse

Specificity: Mouse, Rat, Human

Clone: CBYY-1286

Application*: WB, IP, IF, E

Mouse Anti-VAT1 Recombinant Antibody (3E9) (CBMAB-1303-YY)

Datasheet

SDS

Target: VAT1

Host: Mouse

Specificity: Human

Clone: 3E9

Application*: WB, IP, E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)