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VAT1

Synaptic vesicles are responsible for regulating the storage and release of neurotransmitters in the nerve terminal. The protein encoded by this gene is an abundant integral membrane protein of cholinergic synaptic vesicles and is thought to be involved in vesicular transport. It belongs to the quinone oxidoreductase subfamily of zinc-containing alcohol dehydrogenase proteins. [provided by RefSeq]

Full Name

vesicle amine transport protein 1 homolog (T. californica)

Function

Possesses ATPase activity (By similarity).
Plays a part in calcium-regulated keratinocyte activation in epidermal repair mechanisms. Has no effect on cell proliferation. Negatively regulates mitochondrial fusion in cooperation with mitofusin proteins (MFN1-2).

Biological Process

Biological Process negative regulation of mitochondrial fusion Source:UniProtKB1 Publication

Cellular Location

Cytoplasm
Mitochondrion outer membrane
The majority is localized in the cytoplasm and a small amount is associated with mitochondria.

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Anti-VAT1 antibodies

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Mouse Anti-VAT1 Recombinant Antibody (CBYY-1554) (CBMAB-1624-YY)

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Target: VAT1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBYY-1554

Application*: WB, E

Mouse Anti-VAT1 Recombinant Antibody (CBYY-1286) (CBMAB-1304-YY)

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Target: VAT1

Host: Mouse

Specificity: Mouse, Rat, Human

Clone: CBYY-1286

Application*: WB, IP, IF, E

Mouse Anti-VAT1 Recombinant Antibody (3E9) (CBMAB-1303-YY)

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Target: VAT1

Host: Mouse

Specificity: Human

Clone: 3E9

Application*: WB, IP, E

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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