WIF1
The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers. [provided by RefSeq, Jun 2010]
Full Name
WNT Inhibitory Factor 1
Function
Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.
Biological Process
Biological Process anatomical structure development Source:GO_Central1 Publication
Biological Process negative regulation of Wnt signaling pathway Source:ParkinsonsUK-UCL1 Publication
Biological Process positive regulation of fat cell differentiation Source:Ensembl
Biological Process signal transduction Source:ProtInc1 Publication
Biological Process Wnt signaling pathway Source:UniProtKB-KW
Biological Process negative regulation of Wnt signaling pathway Source:ParkinsonsUK-UCL1 Publication
Biological Process positive regulation of fat cell differentiation Source:Ensembl
Biological Process signal transduction Source:ProtInc1 Publication
Biological Process Wnt signaling pathway Source:UniProtKB-KW
Cellular Location
Secreted
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Anti-WIF1 antibodies
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CompareTarget: Wif1
Sensitivity: 0.027 ng/mL
Detection Range: 0.06-18 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Target: WIF1
Sensitivity: 0.01 ng/mL
Detection Range: 0.02-6 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: WIF1
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-379
Tag: His Tag
Target: WIF1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT1301
Application*: WB, P, IF, IC, E
Target: WIF1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4360
Application*: WB, IH, IC
Target: WIF1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJW-232
Application*: WB, IH, P
Target: WIF1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: D50F9
Application*: WB
Target: WIF1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJW-122
Application*: IH, WB
Target: WIF1
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBWJW-103
Application*: WB
Target: WIF1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJW-102
Application*: IH, WB
Target: WIF1
Host: Mouse
Specificity: Human, Mouse, Rat
Clone: CBWJW-038
Application*: WB, IP, IH, IC, F
Target: WIF1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJW-037
Application*: E, WB, IH, IF, IC
Target: WIF1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJW-036
Application*: E, P, WB
Target: WIF1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6D27
Application*: P, WB
Target: WIF1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1G5
Application*: E, IF, IH, P, WB
Target: WIF1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJW-200
Application*: E, IF, IH, WB
Target: WIF1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJW-181
Application*: E, IH, WB
Target: WIF1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBWJW-179
Application*: WB
Target: WIF1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJW-177
Application*: WB, IH
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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