Sign in or Register   Sign in or Register
  |  

Mouse Anti-ADRA2C Recombinant Antibody (V2-12534) (CBMAB-1024-CN)

This product is a mouse antibody that recognizes ADRA2C of human. The antibody S330A-80 can be used for immunoassay techniques such as: WB, IF.
See all ADRA2C antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
V2-12534
Antibody Isotype
IgG1
Application
WB, IF

Basic Information

Immunogen
Synthetic peptide aa. 442- 462 (QDFRRSFKHILFRRRRRGFRQ, cytoplasmic C-terminus) of human Alpha-2C adrenergic receptor.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS pH7.4, 50% glycerol
Preservative
0.09% sodium azide
Concentration
1 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Adrenoceptor Alpha 2C
Introduction
Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
Entrez Gene ID
152
UniProt ID
P18825
Alternative Names
ADRA2L2; ADRARL2; ADRA2RL2; ALPHA2CAR
Function
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
Biological Process
Activation of protein kinase B activity
Adenylate cyclase-activating adrenergic receptor signaling pathway
Adrenergic receptor signaling pathway
Cell-cell signaling
Female pregnancy
G protein-coupled receptor signaling pathway
Negative regulation of epinephrine secretion
Negative regulation of norepinephrine secretion
Negative regulation of uterine smooth muscle contraction
Platelet activation
Positive regulation of MAPK cascade
Positive regulation of neuron differentiation
Positive regulation of vasoconstriction
Receptor transactivation
Regulation of insulin secretion
Regulation of sensory perception of pain
Cellular Location
Cell membrane
Topology
Extracellular: 1-51 aa
Helical: 52-76 aa
Cytoplasmic: 77-88 aa
Helical: 89-114 aa
Extracellular: 115-124 aa
Helical: 125-147 aa
Cytoplasmic: 148-168 aa
Helical: 169-191 aa
Extracellular: 192-207 aa
Helical: 208-231 aa
Cytoplasmic: 232-379 aa
Helical: 380-407 aa
Extracellular: 408-420 aa
Helical: 421-441 aa
Cytoplasmic: 442-462 aa
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-ADRA2C Recombinant Antibody (V2-12534)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare