Human ADRA2C ELISA Kit (V2LY-0626-LY5593)

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Tested Data
Datasheet
SDS
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Basic Information

Sensitivity
0.013 ng/mL
Detection Range
0.02-4.5 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
49.5 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Adrenoceptor Alpha 2C
Function
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
Biological Process
Activation of protein kinase B activity
Adenylate cyclase-activating adrenergic receptor signaling pathway
Adrenergic receptor signaling pathway
Cell-cell signaling
Female pregnancy
G protein-coupled receptor signaling pathway
Negative regulation of epinephrine secretion
Negative regulation of norepinephrine secretion
Negative regulation of uterine smooth muscle contraction
Platelet activation
Positive regulation of MAPK cascade
Positive regulation of neuron differentiation
Positive regulation of vasoconstriction
Receptor transactivation
Regulation of insulin secretion
Regulation of sensory perception of pain
Cellular Location
Cell membrane
Topology
Extracellular: 1-51 aa
Helical: 52-76 aa
Cytoplasmic: 77-88 aa
Helical: 89-114 aa
Extracellular: 115-124 aa
Helical: 125-147 aa
Cytoplasmic: 148-168 aa
Helical: 169-191 aa
Extracellular: 192-207 aa
Helical: 208-231 aa
Cytoplasmic: 232-379 aa
Helical: 380-407 aa
Extracellular: 408-420 aa
Helical: 421-441 aa
Cytoplasmic: 442-462 aa

Aharon, D., Friedman, E. G., Overbey, J. R., McLaughlin, M. A., Langaee, T., & Thurston, R. C. (2019). The association of an alpha2C adrenoreceptor gene polymorphism with vasomotor symptoms in African American women. Menopause (New York, NY), 26(3), 300.

Schmutz, I., Jagannathan, V., Dìez Bernal, S., Lanz, S., Kalbfleisch, T., Leeb, T., & Spadavecchia, C. (2018). Exclusion of adrenoceptor alpha 2 variants in a horse insensitive to medetomidine. Animal genetics, 49(2), 141.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-ADRA2C Recombinant Antibody (V2-12534) (CAT#: CBMAB-1024-CN)

Mouse Anti-ADRA2C Recombinant Antibody (V2-180024) (CAT#: CBMAB-A1417-YC)

Isotype control

For research use only. Not intended for any clinical use.

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