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Mouse Anti-ASF1A Recombinant Antibody (CBT4630) (V2LY-0625-LY804)


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Tested Data
Mouse Anti-ASF1A Recombinant Antibody (CBT4630) (V2LY-0625-LY804) in ELISA
Mouse Anti-ASF1A Recombinant Antibody (CBT4630) (V2LY-0625-LY804) in ELISA
Mouse Anti-ASF1A Recombinant Antibody (CBT4630) (V2LY-0625-LY804) in WB
Mouse Anti-ASF1A Recombinant Antibody (CBT4630) (V2LY-0625-LY804) in WB
Mouse Anti-ASF1A Recombinant Antibody (CBT4630) (V2LY-0625-LY804) in WB
Mouse Anti-ASF1A Recombinant Antibody (CBT4630) (V2LY-0625-LY804) in WB
Mouse Anti-ASF1A Recombinant Antibody (CBT4630) (V2LY-0625-LY804) in FC
Mouse Anti-ASF1A Recombinant Antibody (CBT4630) (V2LY-0625-LY804) in FC

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBT4630
Antibody Isotype
IgG1
Application
FC

Basic Information

Immunogen
Purified recombinant fragment of human ASF1A (AA: 1-204) expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
FC1:200-1:400
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Entrez Gene ID
25842
UniProt ID
Q9Y294
Function
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
Biological Process
DNA repair Source: MGI
DNA replication-dependent nucleosome assembly Source: UniProtKB
DNA replication-independent nucleosome assembly Source: UniProtKB
Muscle cell differentiation Source: Ensembl
Negative regulation of chromatin silencing Source: UniProtKB
Nucleosome assembly Source: MGI
Osteoblast differentiation Source: Ensembl
Cellular Location
Nucleus
PTM
Phosphorylated by TLK1 and TLK2. Highly phosphorylated in S-phase and at lower levels in M-phase. TLK2-mediated phosphorylation at Ser-192 prevents proteasome-dependent degradation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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