Mouse Anti-ASPSCR1 Recombinant Antibody (CBT3207) (V2LY-0625-LY2080)

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Tested Data
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
CBT3207
Application
WB
Immunogen
Purified recombinant fragment of TUG expressed in E. Coli.
Host Species
Mouse
Specificity
Mouse
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Preservative
Sodium azide
Concentration
Batch dependent
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
ASPSCR1, UBX Domain Containing Tether For SLC2A4
Entrez Gene ID
UniProt ID
Function
Tethering protein that sequesters GLUT4-containing vesicles in the cytoplasm in the absence of insulin. Modulates the amount of GLUT4 that is available at the cell surface (By similarity).
Enhances VCP methylation catalyzed by VCPKMT.
Biological Process
Glucose homeostasis Source: Ensembl
Intracellular protein transport Source: Ensembl
Positive regulation of protein modification process Source: UniProtKB
Regulation of glucose import Source: Ensembl
Cellular Location
Cytoplasm; Nucleus; Endomembrane system; Endoplasmic reticulum-Golgi intermediate compartment membrane

Wang, S., Pozner, A., Neison, M., Jones, K., & Shen, P. (2021). The role of the ASPL-TFE3 fusion protein in Alveolar Soft Part Sarcoma. Microscopy and Microanalysis, 27(S1), 1114-1116.

Coyne, G. O. S., Naqash, A. R., Sankaran, H., & Chen, A. P. (2021). Advances in the management of alveolar soft part sarcoma. Current problems in cancer, 45(4), 100775.

Yoshimatsu, Y., Noguchi, R., Tsuchiya, R., Sei, A., Sugaya, J., Fukushima, S., ... & Kondo, T. (2020). Establishment and characterization of NCC-ASPS1-C1: a novel patient-derived cell line of alveolar soft-part sarcoma. Human Cell, 33(4), 1302-1310.

Whaley, R. D., & Thompson, L. D. (2020). Primary thyroid gland alveolar soft part sarcoma. Head and neck pathology, 14(3), 701-706.

Dumont, S. N., Orbach, D., Coulomb-L’herminé, A., & Robin, Y. M. (2020). Alveolar Soft Part Sarcoma. In Rare Sarcomas (pp. 91-112). Springer, Cham.

Principe, D. R., Mohindra, N. A., Munshi, H. G., & Kamath, S. D. (2019). Alveolar soft part sarcoma mimics prostate cancer metastasis. Oxford medical case reports, 2019(12), 507-509.

Soheilifar, M. H., Taheri, R. A., Emameh, R. Z., Moshtaghian, A., Kooshki, H., & Motie, M. R. (2018). Molecular landscape in alveolar soft part sarcoma: implications for molecular targeted therapy. Biomedicine & Pharmacotherapy, 103, 889-896.

Rhee, D. S., Dunkel, I. J., Shukla, N. N., Walsh, M. F., Gilheeney, S. W., Price, A. P., ... & Heaton, T. E. (2017). Alveolar soft part sarcoma of the bladder with ASPSCR1-TFE3 gene fusion as a secondary malignancy. Journal of Pediatric Surgery Case Reports, 27, 19-22.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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