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ASPSCR1 Matched Antibody Pair (111) (APMAB-111LY)

This antibody pair set can be used for detecting and quantifying protein level of human ASPSCR1.
See all ASPSCR1 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-ASPSCR1 monoclonal antibody, 100 ug
Detection Antibody
Anti-ASPSCR1 Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Oct 2011]
Alternative Names
ASPSCR1, UBX Domain Containing Tether For SLC2A4; Alveolar Soft Part Sarcoma Chromosomal Region Candidate Gene 1 Protein; Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1; Renal Papillary Cell Carcinoma Protein 17; Tether Containing UBX Domain For GLUT4; Alveolar Soft Part Sarcoma Locus; UBX Domain-Containing Protein 9; UBX Domain Protein 9; RCC17;
Entrez Gene ID
79058
UniProt ID
Q9BZE9

Wang, S., Pozner, A., Neison, M., Jones, K., & Shen, P. (2021). The role of the ASPL-TFE3 fusion protein in Alveolar Soft Part Sarcoma. Microscopy and Microanalysis, 27(S1), 1114-1116.

Coyne, G. O. S., Naqash, A. R., Sankaran, H., & Chen, A. P. (2021). Advances in the management of alveolar soft part sarcoma. Current problems in cancer, 45(4), 100775.

Yoshimatsu, Y., Noguchi, R., Tsuchiya, R., Sei, A., Sugaya, J., Fukushima, S., ... & Kondo, T. (2020). Establishment and characterization of NCC-ASPS1-C1: a novel patient-derived cell line of alveolar soft-part sarcoma. Human Cell, 33(4), 1302-1310.

Whaley, R. D., & Thompson, L. D. (2020). Primary thyroid gland alveolar soft part sarcoma. Head and neck pathology, 14(3), 701-706.

Dumont, S. N., Orbach, D., Coulomb-L’herminé, A., & Robin, Y. M. (2020). Alveolar Soft Part Sarcoma. In Rare Sarcomas (pp. 91-112). Springer, Cham.

Principe, D. R., Mohindra, N. A., Munshi, H. G., & Kamath, S. D. (2019). Alveolar soft part sarcoma mimics prostate cancer metastasis. Oxford medical case reports, 2019(12), 507-509.

Soheilifar, M. H., Taheri, R. A., Emameh, R. Z., Moshtaghian, A., Kooshki, H., & Motie, M. R. (2018). Molecular landscape in alveolar soft part sarcoma: implications for molecular targeted therapy. Biomedicine & Pharmacotherapy, 103, 889-896.

Rhee, D. S., Dunkel, I. J., Shukla, N. N., Walsh, M. F., Gilheeney, S. W., Price, A. P., ... & Heaton, T. E. (2017). Alveolar soft part sarcoma of the bladder with ASPSCR1-TFE3 gene fusion as a secondary malignancy. Journal of Pediatric Surgery Case Reports, 27, 19-22.

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For research use only. Not intended for any clinical use.

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