Sign in or Register   Sign in or Register
  |  

Rabbit Anti-CAMLG Recombinant Antibody (D5L9J) (CBMAB-CP0089-LY)

The product is antibody recognizes CAMLG. The antibody D5L9J immunoassay techniques such as: WB,IP.
See all CAMLG antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat, Hamster, Monkey
Clone
D5L9J
Antibody Isotype
IgG
Application
WB, IP

Basic Information

Immunogen
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Leu110 of human CAMLG protein.
Specificity
Human, Mouse, Rat, Hamster, Monkey
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
100 µg/ml BSA, 50% glycerol
Preservative
0.02% sodium azide
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Calcium Modulating Ligand
Introduction
CAMLG (Calcium Modulating Ligand) is a Protein Coding gene. Diseases associated with CAMLG include Cogan-Reese Syndrome. Among its related pathways are RANK Signaling in Osteoclasts and Ca, cAMP and Lipid Signaling. Gene Ontology (GO) annotations related to this gene include cell adhesion molecule binding.
Entrez Gene ID
Human819
Mouse12328
Rat81715
Hamster101832122
Monkey711188
UniProt ID
HumanP49069
MouseP49070
RatQ6DGG9
HamsterA0A1U7R0D1
MonkeyA0A0D9RLY0
Alternative Names
Calcium Modulating Ligand; Calcium-Modulating Cyclophilin Ligand; Cyclophilin B-Binding Protein; CAML; Calcium-Signal Modulating Cyclophilin Ligand; Calcium Signal-Modulating Cyclophilin Ligand; GET2;
Function
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum (PubMed:23041287, PubMed:24392163, PubMed:27226539).
Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol (PubMed:23041287, PubMed:24392163, PubMed:27226539).
Required for the stability of GET1 (PubMed:32187542).
Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium (PubMed:7522304).
Essential for the survival of peripheral follicular B cells (By similarity).
Biological Process
B cell homeostasis Source: UniProtKB
Defense response Source: ProtInc
Negative regulation of proteasomal ubiquitin-dependent protein catabolic process Source: UniProtKB
Negative regulation of protein ubiquitination Source: UniProtKB
Protein stabilization Source: UniProtKB
Signal transduction Source: ProtInc
Tail-anchored membrane protein insertion into ER membrane Source: UniProtKB
Viral process Source: UniProtKB-KW
Cellular Location
Endoplasmic reticulum membrane
Topology
Cytoplasmic: 1-189 aa
Helical: 190-207 aa
Lumenal: 208-212 aa
Helical: 213-231 aa
Cytoplasmic: 232-269 aa
Helical: 270-288 aa
Lumenal: 289-296 aa
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Rabbit Anti-CAMLG Recombinant Antibody (D5L9J)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare