Human Anti-CD52 Recombinant Antibody (CBXC-0724) (CBMAB-C1838-CQ)

Frota, N. F., de Sousa Rebouças, A., Fuzo, C. A., & Lourenzoni, M. R. (2021). Alemtuzumab scFv fragments and CD52 interaction study through molecular dynamics simulation and binding free energy. Journal of Molecular Graphics and Modelling, 107949.

Mao, R., Yang, F., Zhang, Y., Liu, H., Guo, P., Liu, Y., & Zhang, T. (2021). High expression of CD52 in adipocytes: a potential therapeutic target for obesity with type 2 diabetes. Aging (Albany NY), 13(8), 11043.

Wang, J., Zhang, G., Sui, Y., Yang, Z., Chu, Y., Tang, H., ... & Wu, C. (2020). CD52 Is a Prognostic Biomarker and Associated With Tumor Microenvironment in Breast Cancer. Frontiers in Genetics, 11, 1350.

Bhamidipati, K., Silberstein, J. L., Chaichian, Y., Baker, M. C., Lanz, T. V., Zia, A., ... & Robinson, W. H. (2020). CD52 is Elevated on B cells of SLE Patients and Regulates B Cell Function. Frontiers in Immunology, 11, 3736.

Shathili, A. M., Bandala-Sanchez, E., John, A., Goddard-Borger, E. D., Thaysen-Andersen, M., Everest-Dass, A. V., ... & Packer, N. H. (2019). Specific sialoforms required for the immune suppressive activity of human soluble CD52. Frontiers in immunology, 10, 1967.

Zheng, C., Zhuang, C., Chen, Y., Fu, Q., Qian, H., Wang, Y., ... & Qi, N. (2018). Improved process robustness, product quality and biological efficacy of an anti-CD52 monoclonal antibody upon pH shift in Chinese hamster ovary cell perfusion culture. Process Biochemistry, 65, 123-129.

Simon, M., Ipek, R., Homola, G. A., Rovituso, D. M., Schampel, A., Kleinschnitz, C., & Kuerten, S. (2018). Anti-CD52 antibody treatment depletes B cell aggregates in the central nervous system in a mouse model of multiple sclerosis. Journal of neuroinflammation, 15(1), 1-15.

Rashidi, M., Bandala-Sanchez, E., Lawlor, K. E., Zhang, Y., Neale, A. M., Vijayaraj, S. L., ... & Harrison, L. C. (2018). CD52 inhibits Toll-like receptor activation of NF-κ B and triggers apoptosis to suppress inflammation. Cell Death & Differentiation, 25(2), 392-405.

Bandala-Sanchez, E., Bediaga, N. G., Goddard-Borger, E. D., Ngui, K., Naselli, G., Stone, N. L., ... & Harrison, L. C. (2018). CD52 glycan binds the proinflammatory B box of HMGB1 to engage the Siglec-10 receptor and suppress human T cell function. Proceedings of the National Academy of Sciences, 115(30), 7783-7788.

Zhao, Y., Su, H., Shen, X., Du, J., Zhang, X., & Zhao, Y. (2017). The immunological function of CD52 and its targeting in organ transplantation. Inflammation Research, 66(7), 571-578.

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols