Sign in or Register   Sign in or Register
  |  

Mouse Anti-CDKN2D Recombinant Antibody (2E10) (CBMAB-C4953-LY)

This product is antibody recognizes CDKN2D. The antibody 2E10 immunoassay techniques such as: ELISA, IP, WB.
See all CDKN2D antibodies
Published Data
Fig.1 Differentiated SH-SY5Y cells were transfected with an antisense oligodeoxynucleotide to CDK5 (CDK5AS) or to CDK2 (CDK2AS) or their respective scrambled sequence (Scr).
...View More
Fig.2 Retroviral transduction of PVCs with MSCV-RFP (top panel) or MSCV-Arf (bottom panel).
...View More
Fig.3 The levels of endogenous p19 and transfected CDK5 and p35/p25 were also controlled by Western blot.
...View More
Fig.4 Cell lysates were prepared at the indicated times following DNA damage treatment and the expression of p19 protein was analyzed by Western blot.
...View More
Fig.5 Representative Western blot showing induction of p21, p53 and MDM2 upon ectopic p19Arf expression.
...View More

Summary

Host Animal
Mouse
Specificity
Human
Clone
2E10
Antibody Isotype
IgG2b, κ
Application
ELISA, IP, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Cyclin Dependent Kinase Inhibitor 2D
Entrez Gene ID
1032
UniProt ID
P55273
Alternative Names
Cyclin Dependent Kinase Inhibitor 2D; Cyclin-Dependent Kinase Inhibitor 2D (P19, Inhibits CDK4); P19-INK4D; Cell Cycle Inhibitor, Nur77 Associating Protein; Cyclin-Dependent Kinase 4 Inhibitor D P19; Inhibitor Of Cyclin-Dependent Kinase 4d;
Function
Interacts strongly with CDK4 and CDK6 and inhibits them.
Biological Process
Autophagic cell death Source: BHF-UCL
Cell cycle arrest Source: BHF-UCL
DNA synthesis involved in DNA repair Source: BHF-UCL
G1/S transition of mitotic cell cycle Source: BHF-UCL
Negative regulation of cell growth Source: BHF-UCL
Negative regulation of cell population proliferation Source: BHF-UCL
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Source: BHF-UCL
Negative regulation of G1/S transition of mitotic cell cycle Source: Reactome
Negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage Source: BHF-UCL
Negative regulation of phosphorylation Source: BHF-UCL
Regulation of cyclin-dependent protein serine/threonine kinase activity Source: BHF-UCL
Response to retinoic acid Source: BHF-UCL
Response to UV Source: BHF-UCL
Response to vitamin D Source: BHF-UCL
Sensory perception of sound Source: Ensembl
Cellular Location
Nucleus; Cytoplasm
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-CDKN2D Recombinant Antibody (2E10)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare