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Rabbit Anti-CDON Recombinant Antibody (CBFYC-1657) (CBMAB-C1718-FY)

This product is rabbit antibody that recognizes CDON. The antibody CBFYC-1657 can be used for immunoassay techniques such as: ELISA.
See all CDON antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBFYC-1657
Antibody Isotype
IgG
Application
ELISA

Basic Information

Immunogen
Recombinant Human CDON protein
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Cell Adhesion Associated, Oncogene Regulated
Introduction
SHH signaling is regulated by a network of ligand-binding factors, including the primary receptor PTCH1 and the putative coreceptors, CDON (also called CDO), BOC, and GAS1.
Entrez Gene ID
50937
UniProt ID
Q4KMG0
Alternative Names
Cell Adhesion Associated, Oncogene Regulated; Cell Adhesion Molecule-Related/Down-Regulated By Oncogenes; CDO; Surface Glycoprotein, Ig Superfamily Member; Cdon Homolog (Mouse); Cdon Homolog; CDON1; HPE11; ORCAM
Function
Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells (By similarity).
Biological Process
Anterior/posterior pattern specification Source: Ensembl
Cell adhesion Source: UniProtKB
Cell fate specification Source: Ensembl
Cerebral cortex development Source: Ensembl
Embryonic body morphogenesis Source: Ensembl
Embryonic retina morphogenesis in camera-type eye Source: Ensembl
Lens development in camera-type eye Source: Ensembl
Myoblast fusion Source: Ensembl
Positive regulation of MAPK cascade Source: Ensembl
Positive regulation of muscle cell differentiation Source: Reactome
Positive regulation of myoblast differentiation Source: InterPro
Positive regulation of neural precursor cell proliferation Source: Ensembl
Positive regulation of neuron differentiation Source: Ensembl
Positive regulation of protein phosphorylation Source: Ensembl
Positive regulation of skeletal muscle tissue development Source: Ensembl
Positive regulation of small GTPase mediated signal transduction Source: Ensembl
Positive regulation of transcription by RNA polymerase II Source: Ensembl
Regulation of protein binding Source: Ensembl
Skeletal muscle satellite cell differentiation Source: Ensembl
Smoothened signaling pathway Source: Ensembl
Cellular Location
Cell membrane
Involvement in disease
Holoprosencephaly 11 (HPE11): A structural anomaly of the brain, in which the developing forebrain fails to correctly separate into right and left hemispheres. Holoprosencephaly is genetically heterogeneous and associated with several distinct facies and phenotypic variability.
Topology
Extracellular: 26-963
Helical: 964-984
Cytoplasmic: 985-1287
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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