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Rat Anti-CDON Recombinant Antibody (CBYY-C0920) (CBMAB-C2357-YY)

This product is rat antibody that recognizes CDON. The antibody CBYY-C0920 can be used for immunoassay techniques such as: ELISA, WB
See all CDON antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBYY-C0920
Antibody Isotype
IgG2a
Application
ELISA, WB

Basic Information

Immunogen
NS0-derived rmCDO extracellular domain
Specificity
Mouse
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Protein G purified
Buffer
0.5 mg/mL
Preservative
50% glycerol, PBS, 5% trehalose
Concentration
Lyophilized
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Cell Adhesion Associated, Oncogene Regulated
Entrez Gene ID
UniProt ID
Function
Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells (By similarity).
Biological Process
Anterior/posterior pattern specification Source: Ensembl
Cell adhesion Source: UniProtKB
Cell fate specification Source: Ensembl
Cerebral cortex development Source: Ensembl
Embryonic body morphogenesis Source: Ensembl
Embryonic retina morphogenesis in camera-type eye Source: Ensembl
Lens development in camera-type eye Source: Ensembl
Myoblast fusion Source: Ensembl
Positive regulation of MAPK cascade Source: Ensembl
Positive regulation of muscle cell differentiation Source: Reactome
Positive regulation of myoblast differentiation Source: InterPro
Positive regulation of neural precursor cell proliferation Source: Ensembl
Positive regulation of neuron differentiation Source: Ensembl
Positive regulation of protein phosphorylation Source: Ensembl
Positive regulation of skeletal muscle tissue development Source: Ensembl
Positive regulation of small GTPase mediated signal transduction Source: Ensembl
Positive regulation of transcription by RNA polymerase II Source: Ensembl
Regulation of protein binding Source: Ensembl
Skeletal muscle satellite cell differentiation Source: Ensembl
Smoothened signaling pathway Source: Ensembl
Cellular Location
Cell membrane
Involvement in disease
Holoprosencephaly 11 (HPE11): A structural anomaly of the brain, in which the developing forebrain fails to correctly separate into right and left hemispheres. Holoprosencephaly is genetically heterogeneous and associated with several distinct facies and phenotypic variability.
Topology
Extracellular: 26-963
Helical: 964-984
Cytoplasmic: 985-1287
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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