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Mouse Anti-CEACAM3 Recombinant Antibody (CBYY-C1840) (CBMAB-C3278-YY)

This product is mouse antibody that recognizes CEACAM3. The antibody CBYY-C1840 can be used for immunoassay techniques such as: ELISA, WB
See all CEACAM3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-C1840
Antibody Isotype
IgG2a
Application
ELISA, WB

Basic Information

Immunogen
Recombinant corresponding to aa35-155 from the extracellular domain of human CEACAM3 expressed in NSO cells (P40198)
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Protein G purified
Buffer
0.5 mg/mL
Preservative
PBS, 5% trehalose
Concentration
Lyophilized
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Carcinoembryonic Antigen Related Cell Adhesion Molecule 3
Entrez Gene ID
1084
UniProt ID
P40198
Alternative Names
Centromere Protein A; Histone H3-Like Centromeric Protein A; Centromere-Specific Histone; Centromere Protein A, 17kDa; Centromere Autoantigen A; CENP-A; Centromere Protein A (17kD); CenH3;
Function
Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis.
Biological Process
Leukocyte migration Source: Reactome
Cellular Location
Membrane
Topology
Extracellular: 35-155
Helical: 156-176
Cytoplasmic: 177-252
PTM
Tyrosine-phosphorylated in response to microbial binding. Tyr-230 and Tyr-241 are both required for phosphorylation to be detected.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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