Search :
Sign in or Register  
Welcome Sign in or Don't have an account?Register

Mouse Anti-CHRM5 Recombinant Antibody (EG684) (CBMAB-EN825-LY)


See all CHRM5 antibodies
Online Inquiry

Summary

Host Animal
Mouse
Specificity
Human
Clone
EG684
Antibody Isotype
IgG1
Application
ELISA, WB

Basic Information

Immunogen
Purified recombinant fragment of human CHRM5 expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:500-1:2,000
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
0.05% sodium azide
Concentration
1 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Cholinergic Receptor Muscarinic 5
Introduction
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels. [provided by RefSeq, Jul 2008]
Entrez Gene ID
1133
UniProt ID
P08912
Alternative Names
Cholinergic Receptor Muscarinic 5; Acetylcholine Receptor, Muscarinic 5; Muscarinic Acetylcholine Receptor M5; HM5;
Function
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Biological Process
Adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway Source: GO_Central
Chemical synaptic transmission Source: GO_Central
Dopamine transport Source: Ensembl
Gastric acid secretion Source: InterPro
G protein-coupled acetylcholine receptor signaling pathway Source: ProtInc
G protein-coupled receptor signaling pathway Source: Reactome
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger Source: GO_Central
Regulation of phosphatidylinositol dephosphorylation Source: Ensembl
Transmission of nerve impulse Source: Ensembl
Cellular Location
Cell membrane; Postsynaptic cell membrane
Topology
Extracellular: 1-29
Helical: 30-53
Cytoplasmic: 54-66
Helical: 67-87
Extracellular: 88-104
Helical: 105-126
Cytoplasmic: 127-146
Helical: 147-169
Extracellular: 170-191
Helical: 192-214
Cytoplasmic: 215-443
Helical: 444-464
Extracellular: 465-478
Helical: 479-498
Cytoplasmic: 499-532
More Infomation
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-CHRM5 Recombinant Antibody (EG684)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Online Inquiry