Mouse Anti-CLEC6A Recombinant Antibody (CBWJC-2790) (V2LY-1206-LY181)
Compare
Online Inquiry
Basic Information
Thr46-Leu209
| Application | Note |
| FC | 0.25 µg/10^6 cells |
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Binding of C.albicans alpha-mannans to this receptor complex leads to phosphorylation of the immunoreceptor tyrosine-based activation motif (ITAM) of FCER1G, triggering activation of SYK, CARD9 and NF-kappa-B, consequently driving maturation of antigen-presenting cells and shaping antigen-specific priming of T-cells toward effector T-helper 1 and T-helper 17 cell subtypes (By similarity).
Recognizes also, in a mannose-dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production (By similarity).
Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptive immune responses (By similarity).
Defense response to fungus Source: UniProtKB
Innate immune response Source: UniProtKB
Positive regulation of cytokine production Source: UniProtKB
Positive regulation of I-kappaB kinase/NF-kappaB signaling Source: UniProtKB
Stimulatory C-type lectin receptor signaling pathway Source: Reactome
Helical: 21-41
Extracellular: 42-209
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon
$30 eGift Card
Submit a review
Loading...
Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Related Products
Mouse Anti-CLEC6A Recombinant Antibody (9j6) (CAT#: V2LY-1206-LY175)
Mouse Anti-CLEC6A Recombinant Antibody (CBXC-2172) (CAT#: V2LY-1206-LY179)
Mouse Anti-CLEC6A Recombinant Antibody (D0104) (CAT#: V2LY-1206-LY177)
Rat Anti-CLEC6A Recombinant Antibody (CBCNC-019) (CAT#: V2LY-1206-LY183)
Rabbit Anti-CLEC6A Recombinant Antibody (CBWJC-2789) (CAT#: V2LY-1206-LY180)
Rat Anti-CLEC6A Recombinant Antibody (CBYCD-130) (CAT#: V2LY-1206-LY174)
Rabbit Anti-CLEC6A Recombinant Antibody (7B45) (CAT#: CBMAB-D0107-YC)
Rat Anti-CLEC6A Recombinant Antibody (CBCNC-018) (CAT#: V2LY-1206-LY182)
Mouse Anti-CLEC6A Recombinant Antibody (ABM2H28) (CAT#: CBMAB-D0103-YC)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
Online InquiryContact us
