Mouse Anti-DEF8 Recombinant Antibody (2H4) (V2LY-0425-LY148)

Name: Mouse Anti-DEF8 Recombinant Antibody (2H4)
SKU: V2LY-0425-LY148
Rating: 5 (1 reviews)

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Datasheet

Summary

Host Animal

Mouse

Specificity

Human, Mouse, Rat

Clone

2H4

Antibody Isotype

IgG2a

Application

WB, FC

Basic Information

Immunogen

Full length human recombinant protein of human DEF8 produced in HEK293T cell.

Host Species

Mouse

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG2a

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	1:500
FC	1:100

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

BSA & Glycerol & PBS

Preservative

Sodium Azide

Concentration

Batch dependent

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

Differentially Expressed In FDCP 8 Homolog

Entrez Gene ID

54849

UniProt ID

Q6ZN54

Function

Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. Involved in bone resorption.

Biological Process

Intracellular signal transduction Source: InterPro
Lysosome localization Source: UniProtKB
Positive regulation of bone resorption Source: UniProtKB
Positive regulation of ruffle assembly Source: UniProtKB

More Infomation

References

Leyton, E., Matus, D., Espinoza, S., Benitez, J. M., Cortés, B. I., Gomez, W., ... & Nassif, M. (2021). DEF8 and autophagy-associated genes are altered in mild cognitive impairment, probable Alzheimer’s disease patients, and a transgenic model of the disease. Journal of Alzheimer's Disease, 82(s1), S163-S178.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Alternative Versions

Mouse Anti-DEF8 Recombinant Antibody (2H4)

Related Products

Mouse Anti-DEF8 Recombinant Antibody (4B6)

Mouse Anti-DEF8 Recombinant Antibody (2H4)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

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