DEF8

DEF8 (Differentially Expressed In FDCP 8 Homolog) is a protein coding gene. And a paralog is PLEKHM1.
Full Name
Differentially Expressed In FDCP 8 Homolog
Function
Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. Involved in bone resorption.
Biological Process
Intracellular signal transduction Source: InterPro
Lysosome localization Source: UniProtKB
Positive regulation of bone resorption Source: UniProtKB
Positive regulation of ruffle assembly Source: UniProtKB
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Anti-DEF8 antibodies

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Mouse Anti-DEF8 Recombinant Antibody (4B6) (V2LY-0425-LY149)

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Target: DEF8
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Rat
Clone: 4B6
Application*: IF, IH, WB, F
Datasheet SDS

Mouse Anti-DEF8 Recombinant Antibody (2H4) (V2LY-0425-LY148)

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Target: DEF8
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Rat
Clone: 2H4
Application*: WB, F
Datasheet SDS

Mouse Anti-DEF8 Recombinant Antibody (4B6) (CBMAB-D0668-YC)

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Target: DEF8
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 4B6
Application*: WB, F, C, IC, IF, P
Datasheet SDS

Mouse Anti-DEF8 Recombinant Antibody (2H4) (CBMAB-D0667-YC)

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Target: DEF8
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2H4
Application*: WB, F
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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