DEF8

DEF8 (Differentially Expressed In FDCP 8 Homolog) is a protein coding gene. And a paralog is PLEKHM1.

Full Name

Differentially Expressed In FDCP 8 Homolog

Function

Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. Involved in bone resorption.

Biological Process

Intracellular signal transduction Source: InterPro
Lysosome localization Source: UniProtKB
Positive regulation of bone resorption Source: UniProtKB
Positive regulation of ruffle assembly Source: UniProtKB

Anti-DEF8 antibodies

Mouse Anti-DEF8 Recombinant Antibody (2H4) (CBMAB-D0667-YC)

Datasheet

SDS

Target: DEF8

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 2H4

Application*: WB, F

Mouse Anti-DEF8 Recombinant Antibody (4B6) (CBMAB-D0668-YC)

Datasheet

SDS

Target: DEF8

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 4B6

Application*: WB, F, C, IC, IF, P

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)