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Mouse Anti-DEF8 Recombinant Antibody (4B6) (CBMAB-D0668-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
4B6
Antibody Isotype
IgG2a
Application
WB, FC, IHC-Fr, ICC, IF, IHC-P

Basic Information

Immunogen
Full length human recombinant protein of human DEF8 (NP_997397) produced in HEK293T cell
Specificity
Human
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Differentially Expressed In FDCP 8 Homolog
Introduction
DEF8 (Differentially Expressed In FDCP 8 Homolog) is a protein coding gene. And a paralog is PLEKHM1.
Entrez Gene ID
54849
UniProt ID
Q6ZN54
Alternative Names
Differentially Expressed In FDCP 8 Homolog; DEF-8; Differentially Expressed In FDCP 8 Homolog (Mouse);
Function
Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. Involved in bone resorption.
Biological Process
Intracellular signal transduction Source: InterPro
Lysosome localization Source: UniProtKB
Positive regulation of bone resorption Source: UniProtKB
Positive regulation of ruffle assembly Source: UniProtKB
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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