Rabbit Anti-DHFR Recombinant Antibody (
9B2) (V2LY-0725-LY1139)

Huang, K., Narumi, T., Zhang, Y., Li, Q., Murugesan, P., Wu, Y., ... & Cai, H. (2021). Targeting MicroRNA-192-5p, a downstream effector of NOXs (NADPH oxidases), reverses endothelial DHFR (dihydrofolate reductase) deficiency to attenuate abdominal aortic aneurysm formation. Hypertension, 78(2), 282-293.

Ammar, Y. A., Abd El-Hafez, S. M., Hessein, S. A., Ali, A. M., Askar, A. A., & Ragab, A. (2021). One-pot strategy for thiazole tethered 7-ethoxy quinoline hybrids: Synthesis and potential antimicrobial agents as dihydrofolate reductase (DHFR) inhibitors with molecular docking study. Journal of Molecular Structure, 1242, 130748.

Wróbel, A., Baradyn, M., Ratkiewicz, A., & Drozdowska, D. (2021). Synthesis, biological activity, and molecular dynamics study of novel series of a trimethoprim analogs as multi-targeted compounds: Dihydrofolate reductase (DHFR) inhibitors and DNA-binding agents. International journal of molecular sciences, 22(7), 3685.

He, J., Qiao, W., An, Q., Yang, T., & Luo, Y. (2020). Dihydrofolate reductase inhibitors for use as antimicrobial agents. European Journal of Medicinal Chemistry, 195, 112268.

Li, H., Li, Q., Zhang, Y., Liu, W., Gu, B., Narumi, T., ... & Cai, H. (2019). Novel treatment of hypertension by specifically targeting E2F for restoration of endothelial dihydrofolate reductase and eNOS function under oxidative stress. Hypertension, 73(1), 179-189.

Teixeira, B. V. F., Teles, A. L. B., Silva, S. G. D., Brito, C. C. B., Freitas, H. F. D., Pires, A. B. L., ... & Castilho, M. S. (2019). Dual and selective inhibitors of pteridine reductase 1 (PTR1) and dihydrofolate reductase-thymidylate synthase (DHFR-TS) from Leishmania chagasi. Journal of enzyme inhibition and medicinal chemistry, 34(1), 1439-1450.

Hussein, E. M., Al-Rooqi, M. M., Abd El-Galil, S. M., & Ahmed, S. A. (2019). Design, synthesis, and biological evaluation of novel N 4-substituted sulfonamides: acetamides derivatives as dihydrofolate reductase (DHFR) inhibitors. BMC chemistry, 13(1), 1-18.

Francesconi, V., Giovannini, L., Santucci, M., Cichero, E., Costi, M. P., Naesens, L., ... & Tonelli, M. (2018). Synthesis, biological evaluation and molecular modeling of novel azaspiro dihydrotriazines as influenza virus inhibitors targeting the host factor dihydrofolate reductase (DHFR). European journal of medicinal chemistry, 155, 229-243.

Nakano, M., Fukami, T., Gotoh, S., & Nakajima, M. (2017). A-to-I RNA editing up-regulates human dihydrofolate reductase in breast cancer. Journal of Biological Chemistry, 292(12), 4873-4884.

Tonelli, M., Naesens, L., Gazzarrini, S., Santucci, M., Cichero, E., Tasso, B., ... & Loddo, R. (2017). Host dihydrofolate reductase (DHFR)-directed cycloguanil analogues endowed with activity against influenza virus and respiratory syncytial virus. European journal of medicinal chemistry, 135, 467-478.

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols