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Mouse Anti-EDC3 Recombinant Antibody (CBFYE-0024) (CBMAB-E0050-FY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYE-0024
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Enhancer Of MRNA Decapping 3
Introduction
This gene encodes a protein that is important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5' to 3' mRNA decay pathway. Mutations in this gene have been identified in human patients with an autosomal recessive form of intellectual disability.
Entrez Gene ID
80153
UniProt ID
Q96F86
Alternative Names
Enhancer Of MRNA Decapping 3; YjeF N-Terminal Domain-Containing Protein 2; LSM16 Homolog (EDC3, S. Cerevisiae); YjeF Domain-Containing Protein 1; YJEFN2; LSM16; YJDC; Enhancer Of MRNA Decapping 3 Homolog (S. Cerevisiae); Enhancer Of MRNA Decapping 3 Homolog
Research Area
Binds single-stranded RNA. Involved in the process of mRNA degradation and in the positive regulation of mRNA decapping. May play a role in spermiogenesis and oogenesis.
Biological Process
Deadenylation-independent decapping of nuclear-transcribed mRNA Source: GO_Central
P-body assembly Source: GO_Central
Cellular Location
P-body. Processing bodies (PB).
Involvement in disease
Mental retardation, autosomal recessive 50 (MRT50):
A form of mental retardation, a disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. MRT50 patients show mild intellectual disability and microcephaly.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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