Mouse Anti-GALNT2 Recombinant Antibody (G1861) (V2LY-1225-LY628)

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Basic Information

Host Animal
Mouse
Clone
G1861
Application
WB, IF
Immunogen
Recombinant Human GALNT2.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
0.5 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
Polypeptide N-Acetylgalactosaminyltransferase 2
Entrez Gene ID
UniProt ID
Function
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region. Involved in O-linked glycosylation of APOC-III, ANGPTL3 and PLTP. It participates in the regulation of HDL-C metabolism (PubMed:27508872, PubMed:32293671).
Biological Process
O-glycan processing Source: GO_Central
Protein maturation Source: BHF-UCL
Protein O-linked glycosylation Source: UniProtKB
Protein O-linked glycosylation via serine Source: BHF-UCL
Protein O-linked glycosylation via threonine Source: BHF-UCL
Cellular Location
Secreted; Golgi stack membrane. Resides preferentially in the trans and medial parts of the Golgi stack. A secreted form also exists.
Topology
Cytoplasmic: 1-6
Helical: 7-24
Lumenal: 25-571
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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