Mouse Anti-GAS2 Recombinant Antibody (CBFYH-0243) (V2LY-1225-LY693)

Name: Mouse Anti-GAS2 Recombinant Antibody (CBFYH-0243)
SKU: V2LY-1225-LY693
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBFYH-0243

Application

Immunogen

Human GAS2.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

Application	Note
IP	1:100-1:200

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

Sodium azide

Concentration

1 mg/ml

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

growth arrest-specific 2

Entrez Gene ID

2620

UniProt ID

O43903

Function

May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process (By similarity).

Biological Process

Actin crosslink formation Source: GO_Central
Antral ovarian follicle growth Source: Ensembl
Apoptotic process Source: ProtInc
Basement membrane organization Source: Ensembl
Cell cycle Source: UniProtKB-KW
Initiation of primordial ovarian follicle growth Source: Ensembl
Ovulation Source: Ensembl
Regulation of cell shape Source: UniProtKB-KW
Regulation of Notch signaling pathway Source: Ensembl

Cellular Location

Stress fiber; Membrane. Component of the microfilament system. Colocalizes with actin fibers at the cell border and along the stress fibers in growth-arrested fibroblasts. Mainly membrane-associated. When hyperphosphorylated, accumulates at membrane ruffles.

PTM

Cleaved, during apoptosis, on a specific aspartic residue by caspases.
Phosphorylated on serine residues during the G0-G1 transition phase.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Anti-GAS2 (AA 1-110) Recombinant Antibody (CBFYH-0243) (CAT#: CBMAB-H1111-FY)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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