Mouse Anti-GAS2 Recombinant Antibody (CBLG1-3140) (V2LY-1225-LY696)

Name: Mouse Anti-GAS2 Recombinant Antibody (CBLG1-3140)
SKU: V2LY-1225-LY696
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBLG1-3140

Application

WB, IP, IF, ELISA, IHC-P

Immunogen

Recombinant human Gas2.

Host Species

Mouse

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

Application	Note
ELISA	1:100-1:1,000
WB	1:100-1:1,000
IP	1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)	1:50-1:500
IHC-P	1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, gelatin

Preservative

Sodium azide

Concentration

0.1 mg/ml

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

growth arrest-specific 2

Entrez Gene ID

Human	2620
Mouse	14453
Rat	499156

UniProt ID

Human	O43903
Mouse	P11862
Rat	G3V857

Function

May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process (By similarity).

Biological Process

Actin crosslink formation Source: GO_Central
Antral ovarian follicle growth Source: Ensembl
Apoptotic process Source: ProtInc
Basement membrane organization Source: Ensembl
Cell cycle Source: UniProtKB-KW
Initiation of primordial ovarian follicle growth Source: Ensembl
Ovulation Source: Ensembl
Regulation of cell shape Source: UniProtKB-KW
Regulation of Notch signaling pathway Source: Ensembl

Cellular Location

Stress fiber; Membrane. Component of the microfilament system. Colocalizes with actin fibers at the cell border and along the stress fibers in growth-arrested fibroblasts. Mainly membrane-associated. When hyperphosphorylated, accumulates at membrane ruffles.

PTM

Cleaved, during apoptosis, on a specific aspartic residue by caspases.
Phosphorylated on serine residues during the G0-G1 transition phase.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Anti-GAS2 Recombinant Antibody (CBLG1-3140) (CAT#: CBMAB-G2124-LY)

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Mouse Anti-GAS2 (AA 1-110) Recombinant Antibody (CBFYH-0243) (CAT#: CBMAB-H1111-FY)

Rabbit Anti-GAS2 Recombinant Antibody (CBLG1-2587) (CAT#: CBMAB-G0208-LY)

Rabbit Anti-GAS2 Recombinant Antibody (CBLG1-2587) (CAT#: V2LY-1225-LY695)

Mouse Anti-GAS2 Recombinant Antibody (CBLG1-3140) (CAT#: CBMAB-G2124-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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