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Mouse Anti-GCHFR Recombinant Antibody (CBLG1-3154) (CBMAB-G2613-LY)

This product is antibody recognizes GCHFR. The antibody CBLG1-3154 immunoassay techniques such as: WB.
See all GCHFR antibodies

Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Human
Clone
CBLG1-3154
Antibody Isotype
IgG
Application
WB

Basic Information

Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
GTP cyclohydrolase I feedback regulator
Introduction
GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide. [provided by RefSeq, Jul 2008]
Entrez Gene ID
Human2644
Mouse320415
Rat171128
UniProt ID
HumanP30047
MouseP99025
RatP70552
Function
Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine.
Biological Process
Negative regulation of biosynthetic process Source: InterPro
Negative regulation of GTP cyclohydrolase I activity Source: GO_Central
Neurotransmitter metabolic process Source: ProtInc
Nitric oxide biosynthetic process Source: ProtInc
Protein-containing complex assembly Source: Ensembl
Cellular Location
Nucleus; Nucleus membrane; Cytosol
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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